Biochemistry - Lecture 2- Cori Cycle and Gluconeogenesis

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10 Terms

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Glycolysis
A metabolic pathway that converts glucose into pyruvate, producing ATP and NADH.
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Pyruvate
The end product of glycolysis, which can be further metabolized under aerobic or anaerobic conditions.
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Substrate-level phosphorylation
The process of generating ATP by the direct transfer of a phosphate group to ADP from a substrate.
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Aldol cleavage
A reaction where a six-carbon sugar is cleaved into two three-carbon sugars by aldolase.
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NADH
Nicotinamide adenine dinucleotide (NAD) reduced, which is produced during glycolysis and used in cellular respiration.
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Pentose Phosphate Pathway
A metabolic pathway parallel to glycolysis, generating NADPH and ribose-5-phosphate for nucleotides.
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Gluconeogenesis
The synthesis of glucose from non-carbohydrate precursors, primarily occurring in the liver.
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Warburg effect
The observation that cancer cells preferentially use glycolysis for energy production, even in the presence of oxygen.
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Lactate
The product formed from pyruvate under anaerobic conditions, which is involved in lactic acid fermentation.
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Triose phosphate isomerase
An enzyme that catalyzes the interconversion between dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.