Microfilament and Microtubule Proteins

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Last updated 3:55 AM on 4/22/26

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25 Terms

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Formin

- affects actin

- nucleates assembly at plus end

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Arp 2/3 complex

- affects actin

- nucleates assembly at minus end

- web-like structure

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Thyomosin

- affects actin

- binds subunits

- blocking assembly

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Profilin

- affects actin

- binds subunits

- speeding elongation

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Tropomodulin

- affects actin

- prevents assembly and disassembly at minus end

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Tropomyosin

- affects actin

- stabilizing filaments

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Cofilin

- affects actin

- binds ADP-actin filaments

- accelerates disassembly

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Gelsolin

- affects actin

- severs filaments

- binds to plus end

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Capping proteins

- affects actin

- prevents assembly and disassembly at plus end

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Fimbrin

arranges actin cytoskeleton in different ways

- filament bundling

- cross-linking

- attachement to membranes

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a-actin

arranges actin cytoskeleton in different ways

- filament bundling

- cross-linking

- attachement to membranes

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Filamin

arranges actin cytoskeleton in different ways

- filament bundling

- cross-linking

- attachement to membranes

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Spectrin

arranges actin cytoskeleton in different ways

- filament bundling

- cross-linking

- attachement to membranes

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ERM

arranges actin cytoskeleton in different ways

- filament bundling

- cross-linking

- attachement to membranes

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y-TuRC

- affects microtubules

- nucleates assembly

- remains associated at minus end

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Augmin

- affects microtubules

- nucleates microtubule branching

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Stathmin

- affects microtubules

- binds subunits

- prevents assembly

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+TIPs

- affects microtubules

- associates with growing pluc end

- links them to other structures (ex: membranes)

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Kinesin-13

- affects microtubules

- induces catastrophe and disassembly

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XMAP215

- affects microtubules

- stabilizes plus end

- promotes rapid microtubule growth

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Katanin

- affects microtubules

- severs microtubules

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MAPs

- affects microtubules

- stabilizes microtubules by binding along slides

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Tau

- affects microtubules

- filament bundling

- cross-linking

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MAP2

- affects microtubules

- filament bundling

- cross-linking

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Plectin

- affects microtubules

- links to intermediate filaments