describe the DNA structure
double helix; twisted ladder
molecules that make up the sides of the "ladder" of DNA
alternating deoxyribose sugars and phosphate groups
molecules that make up the rungs of the ladder of DNA
Adenine, Thymine, Guanine, Cytosine
3 parts of a nucleotide
Nitrogen base, Deoxyribose sugar, Phosphate group
the bond that holds nitrogen bases together in DNA structure
Hydrogen bonds
Explain the differences between DNA and RNA
RNA is a single stranded molecule, The sugar in RNA is ribose which has one more oxygen atom than deoxyribose, RNA contains Uracil instead of Thymine, so U->A
all nitrogenous bases and nitrogen base pairings.
Adenine, Thymine, Guanine, Cytosine (A->T; G->C)
Know the full name for DNA and RNA and the sugars for each.
DNA=> Deoxyribonucleic acid; deoxyribose RNA=> Ribonucleic acid; ribose
Know how to describe/define DNA Replication, Transcription, and Translation
Replication is the process where cells make copies of DNA, to get a cell ready to divide, and to make proteins. Transcription is the process of DNA to RNA; it makes mRNA. Translation is the process of RNA to proteins; the result is tRNA. Translation is in the ribosome
the contributions of Watson, Crick, Franklin to DNA structure.
They are credited to have discovered DNA and give it it's double helix definition
Know the base Uracil - Replaces? Pairs with? Is it a nitrogenous base of DNA or RNA?
Uracil replaces Thymine in RNA, it pairs with Adenine
Know how to create a complementary strand of DNA (know the base pairing “rules”)
A=>T, G=>C
Know the location within the cell for replication, transcription, and translation.
Replication is in the nucleus, the mRNA goes to the cytoplasm, then the process of translation happens in the ribosomes.
When given a strand of DNA, Know how to create a strand of mRNA, tRNA, and code for proteins by reading codons for amino acids (Mystery Organism Lab). See the last page of this study guide for the codon wheel that will be provided on the test.
mRNA=> make a complementary strand to the DNA. (ex: AAU GCU) tRNA=> complement the mRNA (ex: UUA CGA) Codon for Amino Acid=> find the same 3 pair sequence of nitrogen bases from the mRNA (ex: AAU is Asparagine; GCU is Alanine
Genetics
The science of heredity, dealing with resemblances and differences of related organisms resulting from the interaction of their genes and the environment
Gene
The basic unit of heredity that occupies a specific location on a chromosome. Most genes code for a specific protein or segment of protein leading to a particular characteristic or function.
Allele
A variant form, or specific variation of a gene, some genes have a variety of different forms, which are located at the same position, or genetic locus, on a chromosome. Allele is also how a gene is coded, a comparison of genes and their differences, there is always at least 2 alleles
Chromosome vs. (Sister) Chromatid
Chromosome- thread-like structures located in the nucleus of a cell Sister chromatids- identical copies of DNA attached at the centromere
Homozygous vs. Heterozygous
Homozygous- Having 2 identical alleles of a particular gene/ genes Heterozygous- having two different alleles of a particular gene/ genes
Dominant vs. Recessive
Dominant- Allele that wins over the recessive allele Recessive- Still in the gene, just not present
Genotype vs. Phenotype
Genotype- Identifies the alleles related to a single trait, or number of traits; inherited from an organisms parents; not concerned about the expression of a gene, just the pairs Phenotype- Identifies the observable physical properties of an organism; expression of the trait
Autosomes vs. Sex Chromosomes
Autosomes- control the inheritance of all an organism's characteristics, minus sec-related ones Sex Chromosomes- determines the gender
Karyotypes
A karyotype is an individual's collection of chromosomes. The term also refers to a lab technique that produces an image of an individual's chromosomes. The karyotype is used to look for abnormal numbers of structures of chromosomes
Diploid vs. Haploid
Diploid- A cell or organism that contains 2 copies of each chromosome. Humans are diploids Haploid- A cell or organism having 1 set of chromosomes (egg/sperm)
Gamete vs. Zygote
Gamete=> haploid=>one set of chromosomes=>egg/sperm Zygote=>diploid=>2 sets of chromosomes=> fertilization
Fertilization
The union of egg and sperm
Know the total number of chromosomes and the number of pairs of chromosomes in a human cell.
46,23
Know the phases of the Cell Cycle in order.
Interphase, Prophase, Metaphase, Anaphase, Telophase, Cytokinesis
Know the phases of Mitosis in order.
Prophase, Metaphase, Anaphase, Telophase
Know the phase where cells spend most of their time.
interphase
Know the phase where DNA is replicated.
S phase
Know the phase where a cell is preparing for division (mitosis).
Interphase
Know the phase where chromosomes are first visible.
Prophase
Know the phase where the mitotic spindle forms.
Prophase
Know the phase where the mitotic spindle disassembles/disappears.
Telophase
Know the phase where chromosomes split into chromatids and move to opposite poles (centrosomes).
Anaphase
Know the phase where chromosomes line up in the middle of the cell (equatorial plane).
metaphase
Know the phase where the nucleus dissolves.
Prophase
Know the phase where nuclei reform.
Telophase
Know the phase where the cell divides the contents of its cytoplasm.
Cytokinesis
Know the structure that is responsible for moving chromosomes during mitosis.
Mitotic spindle
Know the organelles called centrioles–know the presence in animal cells and their function with the mitotic spindle.
Centrioles-> barrel-shaped things at the ends of the cell, 2 centrioles in animal cells, plant cells don't use centrioles. Helps form the mitotic spindle
Know the structure called cell plate–know the presence in plant cells and the phase that the cell plate is associated with.
Cell plate- associated with metaphase, in the middle of cells right before division