Chapter 12 Anti Infective Drugs

Gram-positive bacteria stain

dark blue to purple

Gram-negative bacteria stain

pink to red

Bactericidal kills

microorganisms

Bacteriostatic inhibits

replication

Antimicrobials Work against a

broad spectrum of microbes

Antibacterials Work only on

bacteria

Most commonly used antibiotic

penicillins

methicillin, cloxacillin, dicloxacillin, oxacillin are all ____________ resistant penicillins

Beta-lactamase

penicillins are Effective against gram-______ bacteria

positive

Amoxicillin

Amoxicillin-Clavulanic acid (Clavamox)

Ampicillin

Ampicillin-sulbactam (Unasyn)

Pen-G

are all

penicillins

Ampicillin is very useful against

leptospirosis

First Generation cephalosporins (Cephalexin, Cefadroxil, Cefazolin) are effective against ___-_____ bacteria

gram-positive

Second Generation cephalosporins (Cefoxitin) are effective against ___-_____ bacteria

gram-negative

Third Generation cephalosporins (Cefovecin, Cefpodoxime, Ceftiofur, Ceftriaxone) are effective against ___-_____ bacteria

gram negative

Cefovecin trade name

Convenia

Ceftiofur trade name

Excede and Naxcel

Ceftriaxone trade name

Rocephin

Cefazolin is a ____ generation that is a common perioperative antibiotic

1st

a long acting injectable that maintains concentrations at the site of infection for up to 2 weeks

Cefovecin

Cefovecin is a ____ generation that tx skin infections in dogs and wounds & abscesses in cats

3rd

Ceftiofur for swine and cattle

excede