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True or False: Mutations may arise from reactive molecules produced during normal metabolism.
True
Environmental mutagen definition
something outside the cell that causes DNA damage
What repair mechanism you use for replication mistake?
mismatch repair
Which repair mechanism removes a damaged base and replaces it?
base excision
Which repair mechanism cuts out an entire damaged DNA segment?
nucleotide excision
A species has 24 chromosomes in its body cells. How many chromosomes would normally be found in its gametes?
12
give examples of Autosomal recessive trait?
Cystic fibrosis, Sickle-cell anemia
give examples of Autosomal dominant trait?
Huntington's disease, Dwarfism
Aneuploidy definition
extra or missing chromosomes
polyploidy definition
extra whole chromosome sets
antigenic drift (virus) definition
small mutations over time
antigenic shift (virus) definition
big change, new strain
what do proto-oncogenes do?
control cell growth/division
what does Hemagglutinin do?
attachment/host recognition
What does Neuraminidase do?
Helps release new viruses
genetic drift definition
random change in allele frequencies
Is HIV DNA or RNA?
RNA
Is HIV enveloped?
yes
What is the enzyme for retriviruses?
reverse transcriptase
T or F: Frameshift mutation would most likely have the greatest effect on protein function
True
A trait is controlled by several genes and is also influenced by nutrition and environment. The trait is best described as
multifactorial
T or F: Gene duplication provides the greatest opportunity for evolution of entirely new gene functions
True
A DNA repair system removes a mismatch-containing DNA segment and then fills in the correct sequence. This is:
mismatch repair
base excision repair definition
damaged single base removed
nucleotide base excision repair definition
removes larger damaged section
linked genes definition
Genes located on the same chromosome
Crossing over breaks up ____ genes
linked genes
crossing over definition
exchange of DNA between homologous chromosomes
macroevolution definition
long-term large-scale changes
microevolution definition
small changes in allele frequencies over time
Are there homologus chromosomes in gametes?
No
When chromosomes form tetrads in meisosis?
during prophase 1
What proteins hold sister chromatids together?
cohesions
What is chiasmata?
overlapping of homologus chromosomes
T or F: Cross over promotes genetic variation
True
What does cross over occur between?
non sister chromatids
What is turner syndrome
nonlethal, lack X chromosome, monosomy
What is klinefelter syndrome
in males, XXY
T or F: XXX females are healthy
True
First level of separation of cell during meiosis?
cytokinesis
What happens in anaphase 2?
centromere splits, separate sister chromatids
monosomy definitiom
lethal on autosomes, baby die
trisomy definition
baby can survive
what is phenotypic ratio always?
3 to 1
what is test cross
use homozygous breeding
What dominance is 50/50 or blend between traits?
incomplete
How many allelecopies can we have in our body?
2
What are pedigrees used for?
to check how trait passed on
IN pedigrees, unaffected is
shaded in
in pedigrees, homozygous recessive is
not shaded in
Are viruses prokaryote or eukaryote?
neither, they are not true cells
t or f: sickle cell alleles have negative consequences
true
t or f: natural selection only factor for evolution
false
t or f: genetic drift reduces genetic variation
true
what cant BSC be applied to?
asexuals and fossils
sympatric speciation definition
geographic overlapping
punctauted eqilibrium definition
long time little change then brief rapid changes
gradualism meaning
small changes build up over long time
t or f: insertion or deletion can lead to frameshift mutation
true
t or f: nonsense mutation worse earlier in gene
true