Blood bank antigen frequencies

Clinically significant antibodies

ABO, Rh, Kell, Kidd, Duffy, S, s, U, Lub

Clinically insignificant antibodies

I, Lewis, M, N, P1, Lua

Frequency of D

85%

Frequency of E

30%

Frequency of e

97%

Frequency of C

70%

Frequency of c

80%

Frequency of K

9%

Frequency of k

99.8%

Frequency of Kpa

2%

Frequency of Kpb

99.9%

Frequency of Jsa

<1%

Frequency of Jsb

>99.9%

Frequency of Fya

66%

Frequency of Fyb

83%

Frequency of Jka

77%

Frequency of Jkb

74%

Frequency of M

78%

Frequency of N

72%

Frequency of S

55%

Frequency of s

89%

Frequency of P1

79%

Frequency of P2

21%

Frequency of Lea

72%

Frequency of Leb

22%

Frequency of Lua

7.6%

Frequency of Lub

99.8%

Frequency of I

99.9%

Frequency of i

<1%

What blood group is associated with delayed transfusion reactions

Kidd

What blood group is destroyed by DTT

Kell

What blood group may exhibit mixed field reactions

Lutheran

What blood group is frequently a cold autoantibody

I

What blood group(s) show dosage?

Kell (sometimes), Duffy, Kidd, P1Pk (variable), M & N

What blood groups are IgG only

Kell, Duffy, Kidd

What blood groups are both IgG and IgM

Lutheran and MNS

What blood groups are IgM only

Lewis, P1Pk

What conditions are associated with autoanti-I

Mycoplasma pneumoniae, cold hemagluttinin disease

Which of the Lutheran antibodies is IgM

Lua

Which of the Lutheran antibodies is IgG

Lub

What of the MNS system is IgG?

S and s

What of the MNS system is IgM?

M and N

What blood group system needs to be negative for U to be negative?

S and s

What genotype is protective against malaria?

Fy a- b-

What antibodies are possible to P1?

None

What antibodies are possible to P2?

Anti-P1

What antibodies are possible to P1k?

Anti-P

What antibodies are possible to P2k?

Anti-P and anti-P1

What antibodies are possible to (little) p?

Anti-PP1Pk

What blood groups are enhanced by enzymes?

Kidd, P1Pk, Lewis