Inherited Genetic diseases

Meiosis

Generation of gametes from germ line cells.

What is a mutation?

A single nucleotide changed

What is a disease

mutations in a gene

What are Inherited mutations caused by?

Dna abnormalities

Acquired mutations

genetic changes not inherited from parents, often due to environmental factors

Genetic Disorders

A condition caused by an abnormality in an individuals DNA

Monogenetic

Mutation in 1 gene

Polygenetic

Mutations in multiple genes

Anueploidy

add or loss of entire chromosome

Big Dna Alterations

Typically not inherited

-deletion/insertion

-amplification

-translocation

Small DNA alterations

can be inherited

-point mutation

-insertion/deletion

What is a mutation in a single gene called?

Mendelian trait

Who is more affected in X linked recessive disorders?

Males

What are traits of a dominant pattern of inheritrance?

dosent skip generations, sexes equally affected

What is CRISPR?

a gene editing tool that can change speific DNA sequences.