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THE QUIZ AFTER THE MIDTERM
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dysphagia
difficulty swallowing; oropharyngeal or esophageal
oropharyngeal dysphagia
cough, choke, regurg food during initation of swallowing
esophageal dysphagia
feels food get ‘‘stuck’’ / globus sensation
what are alarm symptoms of dysphagia
anemia, weight loss and odynophagia
how to diagnose dysphagia?
modified barium, esophagram and endoscopy
how to treat dysphagia?
treat underlying condition, prevent aspiration and help w/ nutrition; speech therapy possibly
what comorbidities can affect swallowing? (dysphagia)
stroke or dementia
GERD
regurg, heartburn, burning chest pain radiating to mouth, epigastric pain, chronic pain, difficulty controlling asthma
erosive esophagitis → GI bleed, anemia
untreated may lead to esophageal strictures, barrett’s esophagus
GERD diagnosis
upper endoscopy
treatment for GERD?
lifestyle mods, PPI (long term use can be assoc. w c. diff)
What is dyspepsia?
epigastric pain lasting more than 1 month, often accompanied by N/V, bloating. H. Pylori can contribute to this dx
clinical manifestations of dyspepsia?
epigastric pain, early satiety, reflux, N/V
dx for dyspepsia?
stool antigen, urease (for h. pylori)
ph monitoring
new onset sx >60 → upper endoscopy
ct/us to rule out other pathologies
tx for dyspepsia
treat h. pylori, ppi therapy; 2nd/3rd line SSRI/SNRI
what are the two types of peptic ulcer dz?
gastric and duodenal
gastric ulcer?
epigastric pain with eating ; pain typically worsens after meals
duodenal ulcer?
improves with eating and is worse on an empty stomach
peptic ulcer dz symptoms?
abd fullness, bloating, N/V, severe ulcers → GI bleed, perforations
dx for peptic ulcer dz?
stool antigen and urease test, upper endoscopy and biopsy
treatment for peptic ulcer dz?
PPI for 8 weeks, stopping NSAIDs; triple or quadruple therapy for h. pylori
triple therapy for h. pylori?
PPI, clarithromycin, amoxicillin/metronidazole
quadruple therapy for h. pylori?
PPI, bismuth, tetracycline, metronidazole
acute diarrhea vs chronic diarrhea?
less than 4 weeks / greater than 4 weeks ; an increase in stools >3 or change in form
diagnostics for diarrhea
stool studies (c. diff)
chronic diarrhea: stool studies, fecal elastase (eval for pancreatic insufficiency), fecal calprotectin (intestinal inflammatory marker)
serologic testing w/ tissue transglutaminase IgA antibody for celiac dz
endoscopy, colonoscopy, biopsy
diarrhea tx?
acute diarrhea → supportive care
chronic diarrhea → tx underlying cause
diverticular dz?
presence of thin walled outpouching of the colonic mucosa and serosa, most commonly found on the left side of the colon
s/s of diverticular dz?
asymptomatic; -itis: acute abd pain, n/v, anorexia, change in bowel habits
diverticular bleed: sudden onset on painless hematochezia, NSAIDs increase risk
complications include perforations, abscess, fistulas, colonic obstruction
dx for diverticular dz
CT abd pelvis w/ IV contrast, colonoscopy after 6-8 weeks, colonoscopy at dx for pts presenting w large bleeds
tx for diverticular dz
acute uncomplicated: outpt abx for 7-8; cipro & flagyl or augmentin
complications: hospitalized
what is colonic ischemia?
sudden reduction in mesenteric blood flow secondary to vasospasms, hypoperfusion or vascular occlusion; typically occur in ‘‘watershed’’ (splenic flexure) areas which is part of the colon between two vascular supplies
s/s of colonic ischemia?
crampy abd pain followed by hematochezia or bloody diarrhea, tenderness over the area of the affected bowel, peritoneal signs suggest transmural infarction and mandate surgical exploration
dx for colonic ischemia?
CBC, CMP, LA, stool studies, CT abd/pelvis w IV contrast, colonoscopy if no response to meds or dx is in question
tx for colonic ischemia?
iv fluids, bowel rest, address underlying etiology; abc for mod to severe; surgery for severe case
what are the two types of inflammatory bowel dz?
crohns dz and ulcerative colitis
what is crohns dz?
transmural inflammation of GI tract can affect anywhere from mouth to anus, patchy in distribution
what is ulcerative colitis?
inflammation of the mucosal layer of the colon, continuous starting from rectum
s/s of IBD?
abd pain, fecal urgency, diarrhea w or w/o blood, weight loss, fever, fatigue
CD pts → fistulas, strictures and perianal dz
extraintestinal sx: arthritis, oral ulcers, uveitis
dx for IBD?
stool studies to r/o infectious causes, cbc, cmp, albumin and inflammatory markers (ESR, CRP)
endoscopy/colonoscopy and biopsy
fecal incontinence dx?
DRE, endoscopy/colonoscopy
tx for fecal incontinence
treat underlying cause, primary tx → behavioral mods, bedside commode, scheduled toileting, bowel habit training
what are early signs of infections in older adults?
exacerbation of chronic illnesses (chf), functional impairments, falls, delirium
older pts tend to have a blunted febrile responses
if a pt has a single temp over 100F, continuous temp of 99F, or two or more readings with 2 degrees F over baseline → requires eval
what happens to the lungs with age?
lung parenchyma loses its elastic recoil, reduced chest wall compliance, loss of alveoli and alveolar ducts which can increase the risk of pneumonia in the setting of functional disability and acute illness
PNA s/s?
fever, cough, chest congestion, pleuritic chest pain (sputum)
what is the atypical presentation of respiratory infections?
fatigue, anorexia, functional decline, new confusion
influenza s/s?
cough, fever, altered mental status, rhinorrhea, myalgia, GI sx
dx for resp infections?
CBC, CMP, blood cx, rapid flu, covid, rsv, CXR, BMP for PNA & CHF
tx for resp infections?
antibiotics, antivirals
CAP for community dwelling adults w/o chronic conditions macrolide/doxycycline
CAP with chronic conditions Macrolide + beta lactam (augmentin)
what is the dx for GI infections?
stool studies, CBC, BMP
what is the tx for c diff?
oral vancomycin, fidaxomicin,
what is not recommended for pts with GI infections?
antimotility agents are not recommended; do supportive care like hydration and electrolyte replenishment
what is the most likely pathogen to cause cellulitis and erysipelas?
group A strep, strep pyogenes
describe erysipelas
distinct, raised well demarcated borders and is more superficial
what is scabies?
itchy primarily at night, pimple like rash in the interwebs of fingers/toes and flexor side of wrists
how to dx skin dz?
CBC, culture, skin scraping and exam under microscope
tx for abscess?
<5cm incision and drainage if pt is clinically stable
tx for erysipelas and cellulitis
cephalexin (keflex), amoxicillin, cefazolin (ancef), dicloxacillin
tx for scabies?
permethrin 5% cream; oral ivermectin
septic arthritis s/s
hot red painful joint with systemic sx (hard to move joint)
dx for joint infections and osteo
joint aspiration, cx, gram stain, cell count, CBC, ESR, CRP, MRI/plain films
tx for joint infections and osteo
long term oral/iv antibiotics, surgical debridement
having less than 21 teeth compromises…
masticatory function and nutritional status
what is gingivitis the earliest form of?
periodontitis
what is gingivitis?
inflammation assoc. w/ hormonal changes, plaque, foreign body; normally reverses with no lasting damage, can progress to periodontitis
what is periodontitis?
inflammatory destruction of periodontal ligament and bone attached to the tooth root, leads to loss of alveolar bone around teeth → tooth loss
what are dental caries?
oral bacteria colonize exposed tooth surfaces, metabolize carbs, and release acids that demineralize tooth surfaces, potentially leading to a cavity
when can caries destroy the structural integrity of a tooth?
before the patient experiences pain
tx for dental caries?
silver diamine fluoride and fluoride varnish applications and from rx strength high fluoride toothpaste
what is the most common type of oral/pharyngeal malignancies?
squamous cell carcinomas are 96%
s/s of oral cancer?
leukoplakia and erythroplakia persisting for more than 2 weeks, progressing to raised plaques of mixed appearance and ulceration should be referred for biopsy
when should the elderly have dental screenings?
annually
what is xerostomia?
a condition of salivary gland hypofunction
what dz is xerostomia assoc w?
sjogrens, rheumatic dz, head and neck radiation
what happens to saliva during normal aging?
the amount of saliva is stable but it gets thicker
what are meds that cause dry mouth?
TCAs, antihistamines, diuretics, antihypertensives, PPIs
s/s of HIV?
fever, lymphadenopathy, pharyngitis, generalized maculopapular rash, fatigue
what s/s should prompt testing for HIV in older pts
frequent bacterial pneumonia, thrush, neurocognitive changes
dx for HIV?
4th gen HIV antigen/antibody Ag/Ab combo immunoassay → nucleic acid amplification test to detect HIV RNA which helps to confirm acute infection
tx for hiv?
antiretroviral therapy