B. Cardiac Glycosides

Proverbs 16:3

b. Cardiac glycosides

Inhibits the Na⁺/K⁺-ATPase pump, resulting in increased intracellular calcium in cardiac muscle cells.

a. Anthraquinone glycosides

b. Cardiac glycosides

c. Saponin glycosides

d. Cyanogenic glycosides

b. Increased force of cardiac contraction

Positive inotropic effect produced by cardiac glycosides.

a. Decreased heart rate

b. Increased force of cardiac contraction

c. Decreased cardiac output

d. Increased blood viscosity

a. Cardiotonic

Therapeutic effect of cardiac glycosides.

a. Cardiotonic

b. Cathartic

c. Expectorant

d. Keratolytic

c. Cardiotoxic

Toxic effect associated with cardiac glycosides.

a. Hepatotoxic

b. Nephrotoxic

c. Cardiotoxic

d. Neurotoxic

c. Lactone ring

Structural feature used to classify cardiac glycosides.

a. Steroid nucleus

b. Sugar moiety

c. Lactone ring

d. Aromatic ring

b. Cardenolides

Cardiac glycosides possessing a five-membered lactone ring.

a. Bufadienolides

b. Cardenolides

c. Anthraquinones

d. Saponins

b. Cardenolides

Class of cardiac glycosides found predominantly in plants.

a. Bufadienolides

b. Cardenolides

c. Flavonoids

d. Cyanogenic glycosides

a. Bufadienolides

Class of cardiac glycosides found predominantly in animals.

a. Bufadienolides

b. Cardenolides

c. Flavonoids

d. Cyanogenic glycosides

b. Digitalis purpurea

Scientific name of foxglove.

a. Digitalis lanata

b. Digitalis purpurea

c. Nerium oleander

d. Convallaria majalis

b. Digitoxin

Principal cardiac glycoside obtained from foxglove.

a. Digoxin

b. Digitoxin

c. Oleandrin

d. Convallatoxin

b. Digitoxin

Contains a 5-OH group, making it less polar with a longer half-life.

a. Digoxin

b. Digitoxin

c. Oleandrin

d. Scillaren

b. Digitalis lanata

Scientific name of Grecian foxglove.

a. Digitalis purpurea

b. Digitalis lanata

c. Convallaria majalis

d. Urginea maritima

d. Digoxin

Principal cardiac glycoside obtained from Grecian foxglove.

a. Digitoxin

b. Oleandrin

c. Convallatoxin

d. Digoxin

a. Digoxin

Contains a 6-OH group, making it more polar with a shorter half-life

a. Digoxin

b. Digitoxin

c. Oleandrin

d. Convallatoxin

a. Nerium oleander

Scientific name of oleander.

a. Nerium oleander

b. Apocynum cannabinum

c. Convallaria majalis

d. Digitalis purpurea

b. Oleandrin

Principal cardiac glycoside of oleander.

a. Digoxin

b. Oleandrin

c. Convallatoxin

d. Hellebrin

a. Convallaria majalis

Scientific name of lily of the valley.

a. Convallaria majalis

b. Nerium oleander

c. Urginea maritima

d. Helleborus niger

b. Convallatoxin

Principal cardiac glycoside of lily of the valley.

a. Oleandrin

b. Convallatoxin

c. Digoxin

d. Scillaren

a. Apocynum cannabinum

Scientific name of dogbane.

a. Apocynum cannabinum

b. Digitalis lanata

c. Convallaria majalis

d. Urginea maritima

a. Dogbane

Black Indian Hemp is also known as______

a. Dogbane

b. Oleander

c. Squill

d. Foxglove

b. Cynanine

Principal cardiac glycoside of dogbane.

a. Oleandrin

b. Cynanine

c. Convallatoxin

d. Hellebrin

b. K-Strophanthin

Principal cardiac glycoside of Strophanthus kombe.

a. G-Strophanthin

b. K-Strophanthin

c. Digoxin

d. Oleandrin

a. G-Strophanthin

Principal cardiac glycoside of Strophanthus gratus.

a. G-Strophanthin

b. K-Strophanthin

c. Digoxin

d. Oleandrin

a. G-Strophanthin

The chemical compound Ouabain is found in

a. G-Strophanthin

b. K-Strophanthin

c. Digoxin

d. Oleandrin

b. Strophanthus

• Strophanthus gratus

Plant used in the discovery of the Na⁺/K⁺-ATPase pump.

a. Foxglove

b. Strophanthus

c. Squill

d. Dogbane

a. Urginea maritima

Scientific name of squill.

a. Urginea maritima

b. Helleborus niger

c. Apocynum cannabinum

d. Nerium oleander

b. Scillaren

Principal cardiac glycoside of squill.

a. Digoxin

b. Scillaren

c. Oleandrin

d. Hellebrin

c. Scillaren

Cardiac glycoside of squill classified as a bufadienolide.

a. Digitoxin

b. Digoxin

c. Scillaren

d. Convallatoxin

b. Expectorant

Therapeutic use of squill.

a. Cathartic

b. Expectorant

c. Antidepressant

d. Keratolytic

b. Helleborus niger

Scientific name of black hellebore.

a. Convallaria majalis

b. Helleborus niger

c. Digitalis purpurea

d. Nerium oleander

a. Hellebrin

Principal cardiac glycoside of black hellebore.

a. Hellebrin

b. Oleandrin

c. Digoxin

d. Scillaren