lecture 8 neurobiology

These flashcards cover key concepts about neurotransmitter systems from the provided neuroscience lecture notes.

Three criteria for neurotransmitters include synthesis and storage in __ neuron, released by presynaptic axon terminal, and mimicking postsynaptic cell response.

presynaptic

The method used to localize molecules to cells is called __.

Immunocytochemistry

In situ hybridization detects __ in neurons.

mRNA

__ mimics the response of neurotransmitters in postsynaptic cells.

Microiontophoresis

There are three catecholamine neurotransmitters: dopamine, norepinephrine, and __.

epinephrine

GABA mediates most synaptic __ in the CNS.

inhibition

The neuron principle asserts that a neuron has only one __.

neurotransmitter

Selective serotonin reuptake inhibitors (SSRIs) are used as __ to regulate mood.

antidepressants

Ca2+ entry through the NMDA receptor channel triggers biochemical mechanisms that modify __ effectiveness.

synaptic

Synaptic weakening occurs when the postsynaptic cell is only weakly __ by other inputs.

depolarized

The labeled line hypothesis suggests that __ receptor cells exist for each taste stimulus.

individual

The __ of neurotransmitters includes amino acids, amines, and peptides.

evolution

Curare blocks __ receptors, while nicotine activates them.

nicotinic ACh

GABAergic neurons are the major source of __ in the CNS.

synaptic inhibition

The hypothalamus plays an important role in the control of __ and digestion.

feeding

Population coding suggests that large numbers of __ tuned neurons contribute to taste perception.

broadly

The __ receptor for bitter, sweet, or umami flavors utilizes phospholipase C in its transduction mechanism.

G-protein-coupled

Presynaptic calcium influx via NMDA receptors can lead to either LTP or __ dependent processes.

LTD

Choline acetyltransferase (ChAT) is an enzyme critical in the synthesis of __.

acetylcholine

The cerebellum and __ are major regions involved in modulation of neurotransmission.

thalamus

Dale's principle states that a neuron has only one __.

neurotransmitter