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Gastrointestinal (GI) Bleeding
Bleeding from any site between the esophagus and anus
Occult
Hidden
Hematemesis
Vomiting blood
Hematochezia
Gross blood via the rectum
Melena
Black tarry stool
How do you recognize if it is internal?
You DON'T!; Recognize Sx that accompany GI bleed b/c Sx depend on site of bleed
An upper GI bleed occurs where in the GI tract?
Down to and including the duodenum
Pts with an upper GI bleed complain of what Sx? (3)
1. Vomiting bright red blood (Hematemesis)
2. Passing black tarry stools (Melena)
3. Vomiting coffee ground like vomit
A lower GI bleed occurs where in the GI tract?
Remaining small intestine through the colon and to the rectum
Pts with a lower GI bleed complain of what Sx? (1)
1. Passing pure blood or mixed blood with stool (Hematochezia)
Ligament of Treitz
Musculo fibrous band extending from the duodenum to the diaphragm
What does the ligament of Treitz separate?
Upper and lower GI tract
What kind of muscle is the ligament of Treitz and what does it do?
-Suspensory muscle
-Suspends abdominal contents & keeps them in place
What type of bleeding occurs from the esophagus? (2)
1. Vomiting bright red (blood) or coffee ground material
2. Black stools
What is the possible reason of bleeding from the esophagus? (2)
1. Ulcers
2. Varices
What type of bleeding occurs from the stomach? (2)
1. Vomiting bright red (blood) or coffee ground material
2. Black stools
What is the possible reason of bleeding from the stomach? (2)
1. Ulcer
2. Gastritis
What type of bleeding occurs from the small intestine?
Bright red/maroon rectal bleeding
What is the possible reason of bleeding from the small intestine? (2)
1. Ulcer
2. Tumor
What type of bleeding occurs from the large intestine?
Blood in stool
What is the possible reason of bleeding from the large intestine? (3)
1. Colon tumor
2. Polyps
3. Inflammatory Bowel Disease
What type of bleeding occurs from the rectum?
Bright red bleeding
What is the possible reason of bleeding from the rectum? (2)
1. Hemorrhoids
2. Tumor
What do most GI bleeds come from?
Ulcer formation
Risk Factors of GI bleeding (5)
1. Age
2. Chronic use of NSAIDs
3. Prior ulcer
4. Chronic alcohol use
5. Anticoagulants (blood thinners) put Pt at risk
What is the bench mark alcohol "recommendation" for males and females?
Males: 2 drinks/day
Females: 1 drink/day
TRUE OR FALSE: Healthcare providers can force Pts to stop using alcohol.
False, providers can only recommend avoidance of alcohol.
Diagnostics of GI Bleeding (8)
1. Rectal (Digital) Exam
2. FOBT
3. FIT
4. Cologuard
5. Upper endoscopy
6. Drink medium and take scans
7. Sigmoidoscopy
8. Shield Test
What can be observed during a rectal exam?
Lumps, bumps, masses, and tenderness
FOBT
Fecal Occult Blood Test
What is the brand name for FOBT?
Hemocult
What color does the stool turn during an FOBT if it is positive for blood?
Blue
FIT
Fecal Immunochemical Test
What kind of test is an FIT and what can it identify?
-Antibody test
-identifies occult (hidden) blood
How does Cologuard work?
DNA test identifying blood in stool
What part of the GI tract does the upper endoscopy examine?
Mouth to duodenum
What part of the GI tract does a sigmoidoscopy examine?
Rectum to sigmoid
What differentiates a sigmoidoscopy and a colonoscopy?
Sigmoidoscopy: Rectum to sigmoid
Colonoscopy: Rectum to cecum (large intestine)
What does the Shield Test detect?
Detects DNA fragments of cancer in the blood
Diarrhea
Abnormally frequent and liquid stools
Why is "frequent" a deceiving term?
Because defining frequency is based off what is normal for the Pt
Acute diarrhea
Lasts a few days
Chronic diarrhea
Greater than a month
Common causes of diarrhea (7)
1. Viral
2. Bacterial & Parasitic
3. Digestive disorders
4. Medications
5. Use of artificial sweeteners
6. High anxiety and stress
7. Sensitivity to certain foods
What is the #1 cause of diarrhea?
Viral
What is the most common cause of viral diarrhea in the U.S., especially in children?
Norwalk Virus
What is the most common cause of viral diarrhea worldwide?
Rotavirus
Why do we not see Rotavirus in the U.S.?
Kids are vaccinated in the U.S.
What is the transmission mechanism for diarrhea via bacteria and parasites?
Contaminated food or water
What are examples of bacterial causes of diarrhea? (5)
1. Salmonella
2. E. coli
3. Cholera
4. C. diff
5. Shigella
What is the most common bacterial cause of diarrhea?
C. diff
What is an example of a parasitic infection that causes diarrhea?
Giardia lamblia AKA Giardia
Examples of digestive disorders that can cause diarrhea (2)
1. IBS
2. Lactose intolereance
Examples of artificial sweeteners (3)
1. Aspartame
2. Saccharin
3. Sucralose
Pertinent Tests/Exams for diarrhea (5)
1. Detailed Pt Hx
2. Abdominal exam
3. Rectal exam if possible
4. Evaluate dehydration via skin
5. Stool cultures
What kind of questions should health care providers be asking Pts with diarrhea? (4)
1. Recent travel? Especially outside of the U.S.
2. What are you doing differently?
3. Any change in diet?
4. Any new medications?
How can you evaluate for dehydration on P.E.?
Skin tenting and dry mouth
What test would you likely order for a stool culture?
Stool for O & P
-"O" meaning "ova" or eggs
-"P" meaning "parasites"
Tx of Diarrhea (3)
1. Most cases clear up on their own (self-limited)
2. Replace any lost fluid (Pt dehydrated, if severe admit Pt for IV hydration)
3. Extremes of age (young and old, must be overly cautious)
Constipation
Common digestive problem which includes Sx of infrequent (according to Pt normal) BM's, passage of hard stools, or straining during BM
BM
Bowel movement
What happens to the stool, the longer it sits in the colon?
More fluid is absorbed by the large intestine, stool sits in colon, becomes too hard
Sx of constipation (3)
1. Passage of hard stool fewer than 3 times/week
2. Strain frequently during BM
3. Abdominal bloating or discomfort
Contributing factors of constipation (6)
1. Decreased/Inadequate water intake (especially in elderly and peds)
2. Low fiber diet
3. Not responding to bowel urges
4. Lack of physical exercise (sedentary lifestyle)
5. Medication
6. Pregnancy
What kinds of medications contribute to constipation?
1. Narcotics
2. Depression medication
3. Parkinson's medication
Dx testing for constipation (2)
1. Sigmoidoscopy
2. Colonoscopy
Tx of Constipation (3)
1. Lifestyle changes & Pt education (increase water and physical activity)
2. Stool softeners
3. Other Tx will depend on the cause
Colon Cancer
Cancer that arises in the colon (cecum to anus)
How does colon cancer start?
As a polyp that progresses
TRUE OR FALSE: Colon cancer is slow growing.
True
Why is screening so effective in reducing cases of colon cancer?
Due to the slow growth of colon cancer
Sx of colon cancer (6)
1. Rectal bleeding/blood in stools
2. Change in bowel habits
3. Pain with BM
4. None/Asymptomatic (detected by screening)
5. Persistent abdominal gas or discomfort
6. Unexplained weight loss
Which of these Sx is a "red flag"?
Change in bowel habits
Risk factors of colon cancer (9)
1. Age
2. Personal family Hx of colon cancer or polyps
3. Diet
4. Sedentary lifestyle
5. Diabetes
6. Obesity (possible)
7. Smoking (possible)
8. Alcohol
9. Long standing IBD
Types of IBD (2)
1. Crohn's Disease
2. Ulcerative colitis
Dx tests for colon cancer (4)
1. Fecal Occult Blood Test (FOBT)
2. Sigmoidoscopy/Colonoscopy
3. Barium Enema
4. Rectal Exam via P.E.
Tx for colon cancer (3)
1. Surgical excision of cancerous tumor or growth
2. Chemotherapy
3. Radiation
Do all of the Tx for colon cancer have to be given separately, or can they be used in a combination?
Can be used in combination
What does the Tx of colon cancer depend on?
Staging of the cancer
Prevention of colon cancer (5)
1. Regular screening
2. Increase fruits, vegetables, and whole grains in diet
3. Regular exercise
4. Limit alcohol
5. Stop smoking
What age does screening for colon cancer begin at?
45 years old
Stage 0 Colon Cancer
Earliest stage, confined to inner layer of the colon
Stage 1 Colon Cancer
Through mucosa, but not spread beyond colon wall; Still confined and treatable
Stage 2 Colon Cancer
Through colon wall, but not yet spread to lymph nodes
Stage 3 Colon Cancer
Through and to lymph nodes, but not any other body part
Stage 4 Colon Cancer
Spread to distant sites outside the GI tract
What does it mean for the Pt if colon cancer spreads to the lymph nodes?
Becomes more lethal
What are selective sites of metastasis for colon cancer? (3)
1. Liver
2. Lungs
3. Bones
How do we classify cancer staging?
TNM classification
What does the "T" in TNM stand for?
Size and extent of primary tumor (where it began)
What does the "N" in TNM stand for?
Number of nearby lymph nodes that have cancer
What does the "M" in TNM stand for?
Cancer that has metastasized or spread to other sites