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What is the nervous system composed of?
1) brain
2) spinal cord
3) nerves
4) ganglia
5) nervous tissue
What are the 2 cells that make up nervous tissue?
1) neurons
2) glial cells
What are neurons composed of?
-dendrites, cell body, axon
Function of Glial Cells
-support and protect neurons
3 Main Functions of Nervous System
1) Sensory function
2) Processing and integrating function
3) Motor function
Receptors
-belong to sensory function
-monitor change in internal and external environmental stimuli
What 2 body parts process and integrate sensory info?
1) brain
2) spinal cord
Brain and Spinal cord in Motor Function
initiate response as neurons relay motor info to effectors
What do effectors include?
-all 3 muscle tissue
-glands
What are some effects that effectors have?
-can be muscle contraction/relaxation
-change in gland secretion activity
Structural Organization of CNS
-brain enclosed by skull
-spinal cord protected within vertebral canal
Peripheral Nervous System Structural Organization
-nerves
-ganglia
Nerves
bundles of axons of neurons extending from brain and spinal cord
Ganglia
-clusters of neuron cell bodies located along nerves
2 Divisions of nervous system
1) sensory nervous system
2) motor nervous system
Sensory Nervous System (afferent)
-detects stimuli by receptors and relays to the CNS (sensory input)
2 subdivisions of sensory nervous system
-somatic sensory
-visceral sensory
Somatic Sensory
detect stimuli that we consciously perceive
Receptors of Somatic Sensory System
-receptors associated with the 5 senses
-proprioceptors (receptors in muscles, tendons, joints to detect body position)
Visceral Sensory Components
-detect stimuli that we don’t consciously perceive in BVs and internal organs
Examples of Visceral Sensory Detection
-stretch of organ wall
-chemical composition of blood
Motor Nervous System (efferent)
-controls effectors
-initiates and transmits information from CNS to effectors (motor output)
Motor Nervous System 2 Subdivisions
1) somatic
2) visceral
-based upon whether the effector can be controlled consciously
Somatic Motor Component
-initiates and transmits motor output from CNS to skeletal muscles
What is the only effector that can be voluntarily controlled?
-skeletal muscles
Autonomic Motor Component
-innervates and regulates other effectors that can only be involuntary controlled
What are the effectors that are involuntarily controlled?
-cardiac muscle
-smooth muscle
-glands
2 subdivisions of autonomic motor component
-sympathetic division
-parasympathetic division
A nerve is an…?
-organ, 2 or more tissue types work together to perform a function
Fascicle
-bundle axons
-numerous are present within a nerve
What type of muscle tissue are nerves similar to?
-skeletal muscle
3 connective tissue wrappings of nerves
1) epineurium
2) perineurium
3) endoneurium
Epineurium
-thick layer of dense irregular CT enclosing the nerve
-protects and supports entire nerve
Perineurium
-layer of dense irregular CT wrapping each fascicle
-protection and support to bundle of axons
-supports BVs
Endoneurium
-areolar CT surrounding each axon
-separate and electrically insulate each axon
Nerve Vascularization
-branch and extend through epineurium and perineurium to become capillaries in endoneurium
BVs in Nerves Function
-site of exchange of substances between the blood within capillaries and axons
Cranial Nerves
-extend from the brain
-structural classification
Spinal Nerves
-extend from spinal cord
-structural classification
Sensory Nerves
-contain only axons of neurons
-relay info from receptors towards CNS (sensory neurons)
Motor Nerves
-contain axons of neurons
-relay info away from CNS to effectors (motor neurons)
Mixed nerve
-contains both sensory and motor axons (still transmit in their designated directions away/to the CNS)
Nerve
-a bundle of axons in the peripheral nervous system
Ganglion
-cluster of neuron cell bodies in peripheral nervous system (causes swelling)
2 types of ganglia
1) posterior (dorsal) root ganglia associated with sensory neurons extend into spinal cord
2) associate with motor neurons extend to autonomic effectors (cardiac/smooth muscle, glands)
Neuron
-transmit electrical signals
-release neurotransmitters
3 characteristics of neurons
1) excitability
2) conductivity
3) secretion
Excitability
-ability of cell to respond to stimulus
What does a stimulus cause?
- local voltage change in resting membrane potential due to movement of ions across membrane of cell
Conductivity
-voltage changes along membrane as voltage-gated channels open
Secretion
neurons release neurotransmitters in response to conductivity
Neurotransmitters
-molecules stored in vesicles and released when bound to a cell
-excitatory/inhibitory effect
What is excitability associated with?
-dendrites and cell body
What is conductivity associated with?
axon
What is secretion associate with?
-synaptic knobs
Neuron Longevity
-form during fetal development and continue to function over lifetime
Neuron Mitotic Ability
-neurons lose ability to form new cells by mitosis
2 Exceptions of Neuron Mitotic Ability
-neurons in hippocampus
-olfactory epithelium of nose
Neuron Cell Body (Soma) Shape
-spherical shape with cone region called axon hillock
What does the Cell Body house?
-nucleus and cytoplasm
Nucleus in the Cell body
-contains chromatin and nucleolus to synthesize ribosomes
Cytoplasm in Cell Body
-called the perikaryon
-composed of the typical organelles