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afferent
a _______ nerve carries sensory information from the periphery to the central nervous system
amygdala
a brain area critical to learning to recognize threatening situations
anterior
toward the nose
arachnoid mater
one of three meninges that surround and protect the spinal cord and the brain
astrocyte
star shaped glial cells that provide nutrients and other support to nearby neurons
autonomic nervous system
the division of the nervous system that controls the arousal state of internal organs
axon
a thread like extension that leaves the cell body and carries and electrical signal to the terminal
basal ganglia
a brain area important in motor function; damage leads to movement disorders
BOLD (blood oxygenated level-dependent)
a signal used in fMRI brain imaging; increases and decreases in neuronal activity show increases or decreases in this
brain stem
a division of the brain located just atop the spinal cord; contains medulla, pons, cerebellum
caudal
toward the back of the head
cell body
the roundish “factory” of the neuron that contains the cells nucleus and organelles
central canal
a canal running through the spinal cord
central nervous system
the division of the nervous system containing the brain and spinal cord
central sulcus
the groove that separates the frontal from the parietal lobe
cerebellum
a region of the brainstem critical for bodily balance, and for smooth and accurate limb movements
cerebral aqueduct
a fluid filled channel that connects the third and fourth ventricles
cerebral cortex
the thin outer most layer of the brain that is responsible for the complex cognitive processes that define the human species
a chimeric mouse
a mouse that contains some human cells
choroid plexus
a group of cells, located within each of the four ventricles, which produce cerebrospinal fluid
contralateral
opposite side
coronal brain slice
a slice that divides the brain into front and back regions
corpus callosum
a bundle of neurons that connect the two hemispheres
cranial nerves
nerves that communicate directly between the brain and the periphery of the body, bypassing the spinal cord
dendrites
branch like extensions that receive input from other neurons
diencephalon
a division of the brain that lies just above the brainstem; contains the thalamus, hypothalamus, pineal gland, and pituitary gland
dorsal
toward the top of the brain
dura mater
one of three meninges that surround and protect the spinal cord and the brain
efferent nerves
nerves that carry information from the central nervous system to the periphery
forebrain
the portion of the brain above the brainstem
fourth ventricle
one of 4 ventricles of the brain
frontal lobe
a lobe of the cortex most important for movement of the body
glial progenitor cell (GPC)
an immature cell that develops to become a certain type of glial cells
gray matter
tissue made up mostely of cell bodies, dendrites, and unmyelinated axons of neurons
gyri
the hills/bumps that contribute to the crumpled look of the cortex
hippocampus
a key brain structure for storing and recalling memories of personal experiences
horizontal brain slice
a slice that divides the brain into top and bottom regions
hypothalamus
a small brain area that regulates motivated behaviors including sex, eating, thirst, sleep and body temperature
inferior colliculus
a small midbrain region important for orienting and attending to auditory events
lateral
away from the midline of the brain; toward the ear
lateral sulcus
the groove that lies just above the temporal lobe
lateral ventricles
two of the four ventricles of the brain; one on the left and one on the right side of the brain
limbic system
a collection of brain structures significantly involves in emotion and memory
longitudinal fissure
a deep canyon that runs along the midline from the front to the back of the forebrain; separates brain into right and left hemispheres
medial
toward the midline of the brain
medulla
the portion of the brain stem that sits just atop the spinal cord, it governs essential physiological processes such as respiration, sleep, and regulation of blood pressure
microglia
tiny glial cells, when neurons die or suffer damage these glial cells remove the debris left behind
midbrain
region of the brainstem, just above the pons, which contains dopamine neurons
myelin
the whitish tissue that surrounds and insulates axons to speed information transfer across the axon
neurogenesis
the birth of new neurons
neurotransmitter
a chemical released from the axon terminal which crosses a synapse, and binds to receptors
occipital lobe
the lobe of the cerebral cortex dedicated to vision
oligodendrocyte
a glial cell the provides myelin to neurons of the brain and spinal cord
parasympathetic nervous system
division of the autonomic nervous system that restores the resting state of organs and stores energy
parasympathetic ganglia
clusters of parasympathetic nerves that originate close to the organs that they target
parietal lobe
the lobe of the cerebral cortex dedicated principally to touch sensation
peripheral nervous system (PNS)
the division of the nervous system that communicates with the periphery of the body
pia mater
one of three meninges that surrounds and protects the spinal cord and brain
pineal gland
a tiny gland within the diencephalon that plays a role in sleep regulation
pituitary gland
situated just below the hypothalamus; considered the master gland; releases hormones that influence other glands, including those involved in stress and sexual behavior
plasticity
the brains ability to undergo structural and functional change
pons
a brainstem region with a swollen shape; contains neurons that are important in sleep, arousal, respiration, and heart rate
posterior
toward the back of the head
prefrontal cortex
most anterior portion of the frontal lobe; important in cognitive functions—attention and working memory
rostral
toward the nose
sagittal brain slice
slice that divides the left from the right brain
glial cells that provide myelin to neurons of the peripheral nervous system
Schwann cells
somatic nervous system
division of the peripheral nervous system comprised of sensory nerves that carry information to the central nervous system, and motor nerves that carry info from the central nervous system to the skeletal muscles
substantia nigra
small area of the midbrain containing a cluster of dopamine neurons that play a role in movement
sulci
the grooves/valleys that contribute to the crumpled look of the cortex
superior colliculus
a small midbrain region important or orienting and attending to visual events
sympathetic nervous system
the division of the autonomic nervous system that prepares the body for emergency situations
sympathetic ganglia
clusters of sympathetic nerves that originate just outside the spinal cord
synaptic cleft
a tiny gap between the axon terminal of one neuron and receiving areas (receptors) of another neuron
temporal lobe
the lobe of the cerebral cortex that is critical for hearing
terminal (axon terminal)
the ending of an axon, where neurotransmitter is released into a synapse
thalamus
a brain area that acts as a relay to send information to and from the cerebral cortex
third ventricle
one of the four ventricles of the brain
ventral
toward the bottom (of the brain)
VTA
a small region of the midbrain containing a cluster of dopamine neurons involved in reinforcement and addiction
ventricles
the brains four fluid filled chambers, which contain cerebrospinal fluid
white matter
tissue of the nervous system with a whitish appearance due to the white color of myelinated axons
action potential
the successive opening of ion channels, from the initial segment of the axon all the way to the axon terminal
agonist
a drug that mimics or increases the activity of a neurotransmitter
antagonist
a drug that blocks or reduces the effects of a neurotransmitter
autoreceptor
a ________ is a receptor that responds to the neurostransmitter released by its own axon terminal; senses when high levels of neurotransmitters are being released, and causes the neuron to reduce its own firing rate
axon
a thin extension that leaves the cell body and carries an electrical signal to the terminal
axon hillock
the site where the neuron’s cell body gives rise to the axon
blood-brain barrier
a wall of tightly packed cells that surrounds the brain’s blood vessels and allows only certain substances to reach the brain
cell body
the roundish part of the neuron containing the cells nucleus and other cellular machinery
chloride ion (Cl-)
a negatively charged ion concentrated outside the neuron
conduction velocity
the speed with which the action potential moves along the axon
degradation
breaking of a neurotransmitter or other molecule into inactive components, usually by enzymes
depolarization
a change in the neurons membrane potential that makes it less polarized, and more likely to fire
diffusion
the movement of a substance from an area of high concentration to a region of lesser concentration
divergent
neuronal connections that allow a small number of neurons to broadcast a message to many neuronal recipients
electrostatic pressure
the attractive force of opposite charges
enzyme
a protein that can convert one molecule into another
excitatory postsynaptic potential (EPSP)
the size of an excitatory (depolarizing) change in the membrane potential
exocytosis
the merging of a vesicle with the neuron’s membrane and the secretion of its contents into the synaptic cleft