Haematology - Leucocyte Morphology: Granulocytes

BEN IS GREAT! Basophil Eosinophil Neutrophil

Where are Basophils produced?

In the bone marrow, very low numbers within the blood of healthy animals (approx. <1%) 

Appearance of a Basophil

Purple nucleus with blue granules

What do Basophils contain to reduce blood clotting + what do they manufacture?

• Contain heparin to reduce blood clotting 

• Manufacture histamine 

• Promoting blood flow to tissues through vasodilation 

Basophilia is .. and can be caused by .. 

• An abnormal abundance of basophils 

• Allergic reactions and myeloproliferative conditions 

Where are Eosinophils produce and what are there levels within the bloodstream?

• Produced in the bone marrow

• Relatively low numbers within the bloodstream (approx. 4%)

Appearance of Eosinophils

Purple bi-lobed nucleus with red/orange granules

What are Eosinophils involved in? 

Allergic responses and immunity against parasites 

Where are Neutrophils produced?

In the bone marrow and release into the blood stream one mature

What is the dominant leucocyte in dogs and cats?

Full mature neutrophils (approx. 65%)

What is the appearance of Neutrophils?

Segmented purple nucleus and pink pale granules

An increase in the number of circulating ‘band’ immature neutrophils (horse-show shaped nucleus) indicates what?

Acute inflammation or infection

Neutrophils are ..

Phagocytes