Types of mRNA Mutations

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5 Terms

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Synonymus mutation (silent mutation)

A change in the nucleotide sequence that doesn't alter the amino acid sequence of the encoded protein because the mutated codon still codes for the same amino acid

<p><span>A change in the nucleotide sequence that </span><strong>doesn't alter the amino acid sequence of the encoded protein</strong><span> because the </span><strong>mutated codon still codes for the same amino acid</strong></p>
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Nonsense mutation

A type of genetic mutation that introduces a premature stop codon (UAA, UAG, or UGA) into the mRNA sequence, leading to the premature termination of protein synthesis and a truncated, potentially non-functional protein

<p><span>A type of genetic mutation that </span><strong>introduces a premature stop codon (UAA, UAG, or UGA)</strong><span> into the mRNA sequence, </span><strong>leading to the premature termination of protein synthesis</strong><span> and </span><strong>a truncated, potentially non-functional protein</strong></p>
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Missense Mutation

A type of point mutation where a single nucleotide change leads to a different amino acid being incorporated into the protein, resulting in a protein with a potentially altered function

<p><span>A type of </span><strong>point mutation</strong><span> where </span><strong>a single nucleotide change leads to a different amino acid being incorporated</strong><span> into the protein, resulting in a protein with a </span><strong>potentially altered function</strong></p>
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Substitution Mutation

A mutation that exchanges one base for another

<p><span>A mutation that exchanges one base for another</span></p>
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Which are substitution mutations?

1. Missense Mutation
2. Nonsense Mutation
3. Silent Mutation