Route and Characteristic - Pceutics 2

Oral

Which route uses an aqueous formulation with flavors, colors, sweetening agents and a pH of approximately 7 (range 2-9)?

Topical (skin/hair/nail)

Which route uses aqueous or non-aqueous vehicles like lotions, liniments, paints, tinctures, and collodions?

Otic

Which route uses aqueous or non-aqueous formulations with high viscosity?

Ocular

Which route uses sterile aqueous formulations with a pH of ~7.4 (range 3.5-9.0), isotonicity, and high viscosity?

Nasal

Which route uses aqueous formulations with a pH of 5.5-6.5?

Pulmonary

Which route uses solutions in liquefied propellants (pressurized MDI) or aqueous formulations (nebulizers)?

Rectal

Which route uses aqueous or oily formulations (enema)?

Vaginal

Which route uses aqueous formulations?

Parenteral

Which route requires sterile, pyrogen-free formulations, with intravenous being aqueous and intramuscular/subcutaneous being aqueous or non-aqueous, and a pH range of 3-9?

pH 7 (range 2-9)

What is the typical pH range for formulations in the Oral Cavity?

Lotion, liniment, paint, tinctures, collodion

What are some examples of formulations for the Topical route?

High viscosity

What physical property is characteristic of Otic formulations?

Sterile

What is a key characteristic of Ocular formulations?

pH 7.4 (range 3.5-9)

What is the typical pH for Ocular formulations?

Isotonic

What tonicity is required for Ocular formulations?

High viscosity

What physical property is often used in Ocular formulations?

pH 5.5-6.5

What is the typical pH range for Nasal formulations?

Pressurized MDI

What is the solution in liquefied propellant used for the Pulmonary route called?

Nebulizers

What is the aqueous formulation for the Pulmonary route called?

Aqueous or oily formulation

What are the formulation options for the Rectal route (enemas)?

Sterile and pyrogen-free

What are two critical requirements for Parenteral formulations?

Aqueous formulation

What is the formulation option for IV administration?

Aqueous/non-aqueous formulation

What are the formulation options for Intramuscular and Subcutaneous routes?

pH 3-9

What is the acceptable pH range for Parenteral formulations?