hypothalamic / pituitary

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Last updated 2:17 AM on 9/22/26
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4 Terms

1
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somatropin

MOA:

  • GH replacement

SQ, IM

use:

  • increase GH

AE:

  • hyperglycemia

  • bone pain

  • HA

  • visual change

teach:

  • monitor growth/development

  • growth plateaus


2
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octreotide

MOA:

  • GH antagonist

  • act directly on postsynaptic domaine in brain

IM, SQ

use:

  • decrease acute GI/variceal bleed

  • decrease carcinoid tumor

AE:

  • CNS

  • abd cramp

  • gallbladder

  • hypothyroidism

teach

  • stand slow

  • monitor blood glucose


3
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desmopressin/vasopressin

MOA:

  • ADH replacement

IV, IM, Intranasal

use:

  • decrease DM

  • decrease urine output

  • improve fluid and electrolyte

AE

  • SIADH

  • nasal dryness

teach

  • monitor weight and IO

  • monitor electrolyte, sodium


4
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SIADH

Syndrome of Inappropriate Antidiuretic Hormone

body holds too much water

↓ Na⁺ (hyponatremia) → confusion/seizures