Biology 65: Chapter 2.4 - the cell life cycle

1

First gap phase (G1)

2

Synthesis phase (S)

3

second gap phase (G2)

4

prophase

5

metaphase

6

anaphase

7

telophase

8

cytokinesis

9

mitotic phase

10

interphase

G1

growth and normal metabolic roles

S

DNA replication

G2

growth and preparation for mitosis

G0

cell is outside replicative cell cycle

stem cells

immature cells with the ability to develop into one or more types of specialized cells

unipotent

able to develop into only one mature cell type

multipotent

able to differentiate into multiple mature cell types

example of unipotent stem cell

cells that develop into sperm

example of multipotent stem cell

bone marrow cells

pluripotent

able to develop into any type of embryonic or adult cell

example of pluripotent stem cell

embryonic stem cell

advantages of adult stem cells

low controversy, same genome as host

disadvantages of adult stem cells

not pluripotent, few in number, hard to culture

advantages of embryonic stem cells

pluripotent, easier to obtain and culture

disadvantages of embryonic stem cells

controversial