Antiepileptic Drugs action

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Last updated 6:25 PM on 8/26/26
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8 Terms

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Phenytoin (Dilantin)

Sodium channel blocker

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Carbamazepine (Tegretol)

Sodium Channel blocker

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Valproic Acid (Depakene)

Blocks Na channels, suppresses Ca influx, may augment GABA (broad spectrum)

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Oxycarbazepine (Trileptal)

Similar to Carbamazepine- blocks recovery of sodium channels. Better tolerated, fewer drug interactions, more expensive.

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Gabapentinoids—>Gabapentin

Reduces excitatory neurotransmitter release( binds to voltage gated calcium channels)

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Gabapentinoids—> Pregabalin

Reduces excitatory neurotransmitter release (binds to voltage gated calcium channels)

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Levetiracetam (Keppra)

Inhibit burst firing from abnormal cells without affecting normal cells

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Lorazepam (Ativan)

Class: Benzodiazepine

Actions: Enhances GABA activity causing CNS depression; limits spread of seizure activity