[PHARMACEUTICAL CALCULATIONS] PACOP PINK

C

1. A formula for a cough syrup contains 1/8 gr of codeine phosphate per teaspoonful. How many grams of codeine phosphate should be used in preparing 2 pints of the cough syrup?

a. 2.30 g

b. 6.43 g

c. 1.54 g

d. 0.91 g

e. 1.03

A

2. How many grams of KSCN should be used in compounding the following prescription?

Rx Potassium Thiocyanate

Aromatic elixir aa qs

Make a solution to contain 0.2 g?tsp

Disp. 150 mL

Sig: 5 mL in water daily

a. 6 g

b. 8 g c. 2.5 g

d. 12.5 g

e. 7.25

B

3. How many gr of dihydrocodeinone should be used in compounding the following prescription?

Rx Dihydrocodeinone gr 1/12 /tsp

Hydriodic acid syrup

Cherry syrup aa fl oz Iii

Sig: Tsp every 2 hr for cough

a. 6

b. 3

c. 12

d. 1.5

e. 4

D

4. A patient has been instructed to take 15 mL of Vistarel® (hydroxyzine pamoate) oral suspension every six hours four doses daily. How many days will two fluidounce bottles of suspension last?

a. 10

b. 5

c.11

d.6

e.8

A

5. The pediatric dose of cefadroxil is 30 mg/kg/day. A child is receiving a daily dose of two teaspoonfuls of a pediatric cefadroxil suspension based on the body weight. If the child's weight is 18.3 lb, How many milligrams of the drug is the child receiving in each dose?

a.250mg

b.120 mg

c.375 mg

d. 300 mg

e. 200 mg

A

6. A physician prescribes tetracycline suspension for a patient to be taken in doses of two teaspoonfuls 4x a day for four days, and then one teaspoonful 4x a day for two days. How many mL of the suspension should be dispensed to provide the quantity for the prescribed dosage regimen?

a. 200 mL

b. 250 mL

c. 500mL

d.120 mL

e. 300 mL

C

7. If a potassium chloride elixir contains 40 milliequivalents of potassium ion in each 30 mL of elixir, how many mL will provide 15 milliequivalents of potassium ion to the patient?

a. 10.25 mL

b. 15.00 mL

c. 11.25 mL

d.25.00mL

e. 10.75 mL

A

8. What is the percentage of alcohol in the following precription?

Rx Chloroform spirit 50.0 mL (90% alcohol)

Aromatic elixir 150.0 mL (21% alcohol)

Terpin hydrate elixir 300.0 mL

(45% alcohol)

Sig. 5 mL for cough

a. 42.3 %

b.56.75%

c.18.2%

d. 38.7%

e.39.7%

B

10. If 5 mL of a 20% w/v aqueous solution of furosemide is diluted to 10 mL, what will be the final strength of furosemide? 10. If 5 mL of a 20% w/v aqueous solution of furosemide is diluted to 10 mL, what will be the final strength of furosemide?

a. 5

b. 10

c. 15

d. 30

e. 20

C

11. How many milliliters of a 1:20 v/v solution of methyl salicylate in alcohol can be made from 100 mL of 2% v/v solution?

a. 25

b.38

c.40

d.30

e.20

D

12. A physicians order for an IV infusion for a patient weighing 110 lbs calls for a 0.25 mEq of KCl per kg of body weight to be added to 500 mL of D5W. How many mL of a sterile solution containing 50 mEq of KCl per 10 mL should be used in preparing the infusion?

a. 10.0 mL

b. 1.0 mL

c. 1.5 mL

d. 2.5 mL

e. 3.0 mL

B

13. A medication order for an IV infusion for a patient weighing 143 lbs calls for a 0.25 mEq of ammonium chloride per kg body weight to be added to 500 mL 5% dextrose injection. How many mL of a sterile solution containing 100 mEq of ammonium chloride per 25 mL should be used in preparing the infusion?

a. 6.2 mL

b. 4.1 mL

c. 8.0 mL

d. 9.8 mL

e. 5.3 mL

A

14. Prochlorperazine is prescribed for a child whose date of birth is 05/21/2001. If the usual adult dose is 5 mg, how many mg would be administered to the child? The prescription is dated 01/01/2005.

a. 0.625 mg

b. 0.820 mg

c. 0.250 mg

d. 0.500 mg

e. 0.725 mg

C

15. How many mL of Reglan injection (5mg/mL) should be given to a patient who is eight months old? The usual dose of metoclopramide HCl is 10 mg.

a. 1.0 mL

b. 2.0 mL

c. 0.1 mL

d. 0.2 mL

e. 0.01 mL

A

16. The usual dose of Tylenol® is 500 mg qid, prn fever. If Tylenol® is to be prescribed for a two-month old baby, how many mL of Tylenol® drops (80 mg/mL) should be given as a single dose to this patient?

a. 0.08 mL

b. 1.10 mL

c. 0.9 mL

d. 0.05 mL

e. 0.8 mL

D

16. Rx

Keflex® caps 500mg

Sig; 1 cap bid, 7 days

If the pharmacist has only 250 mg capsules in the inventory, how many capsules should be given to the patient?

a. 14

b. 7

c. 21

d. 28

e. 24

D

17. If two pints of a guaifenesin elixir is present in the inventory, how many 4-fluid ounces prescription can be filled?

a. 12

b. 10

c. 5

d. 8

e. 6

A

18. An IV flow rate is set at 48gtt/mL. The infusion set has a drop factor of 15gtt/mL. How many mL of IV fluid will be infused in 8 hrs?

a. 1536 mL

b. 2395 mL

c. 1050 mL

d. 950 ml

C

19. What is the percentage (w/w) of coal tar in the finished product in when 10 g of coal tar is mixed with 200 g of a 5% coal tar ointment?

a. 4

b. 6.8

c.9.5

d. 11.0

A

20. A physician ordered: "Benadryl® 50 mg PO h.s. p.r.n." If the available Benadryl® (diphenydramine HCl) elixir contains 2.5 mg drug in each mL, how many teaspoons will be administered to the patient?

a. 4

b. 6

c. 2

d. 5

e. 3

B

21. Fer-in-sol® drops contain 75 mg ferrous sulfate 0.60 mL of the solution. If a pharmacist dispensed 60 mL of the solution, how many grams of ferrous sulfate were dispensed?'

a. 10

b. 7.5

c. 15

d. 20

e. 9

D

22. If a patient needs one teaspoonful of Amoxil® oral liquid 3x a day for seven days, how many fluidounces of medication should the pharmacist dispense?

a. 12

b. 8

c. 6

d. 3.5

e. 7

A

23. How many liters of 2% w/v Iodine tincture can be made from 78 g of iodine?

a. 3.9

b. 6.2

c. 4.8

d. 12

e. 4.6

A

24. How many apothecary ounces are present in lbs iiss?

a. 30

b. 42

c. 16

d. 9.5

e. 22

B

25. Zovirax® tablets, containing the antiviral drug, acyclovir, are given in a dose of 80 mg/kg for 5 days for treating chickenpox. If the patient weighs 120 lbs, how many ounce(s) of acyclovir would the patient consume if he has to take the full dose prescribed?

a. 1.3

b.0.73

c. 16

d. 9.5

e. 3.5

D

26. If a physician orders "Lanoxin® 0.25 mg p.o. q.d.", how many mL of Lanoxin® (digoxin) elixir containing 50 mcg of digoxin per mL should be used?

a. 15 mL

b. 10 mL

c. 8 mL

d. 5 mL

e. 3 mL

B

27. A patient has been instructed to take Vistarel® (hydroxyzine pamoate) oral suspension every four hours for four doses daily. How many days will a 6 -fluidounce bottle of the suspension last?

a. 2

b. 4.5

c. 7

d. 12

e. 6

C

28. Rx

Phenergan tablets 12.5 mg

Dispense 14 tablets

Sig; q hs

If the pharmacist dispensed 25 mg tablets of phenergan, how many tablets should the patient take at bedtime?

a. 2

b. 1

c. 1/2

d. 1/4

e. 1/3

D

29. Rx

Atropine sulfate 0.2 mg

Sig; Administer IM

If the available atropine vial reads gr 1/150 per mL, how many mL of the injection should be administered?

a. 1.20

b. 0.75

c. 1.43

d. 0.465

e. 1.72

A

30. A medication order calls for Prostigmin® 0.25 mg IM. The only supply of Prostigmin® is 1:200 solutions. How many mL of this solution would contain 0.25 mg?

a. 0.05 mL

b. 0.75

c. 1.43

d. 0.465

e.1.72

B 31. What is the percentage (w/w) of hydrocortisone in the finished product when 50 mg of hydrocortisone is mixed with 10 grams of Cortril® ointment containing 1% hydrocortisone?

a. 0.05 mL

b. 0.5 mL

c. 5 mL

d. 0.25 mL

e. 0.005 mL

D

32. What is the percentage of ZnO in an ointment prepared by mixing 200 grams of an 8% ZnO ointment, 150 grams of a 12% ZnO ointment, and 300 grams of white petrolatum (diluent)?

a. 2.3%

b. 4.5%

c. 7.8%

d. 5.23%

e. 2.3 %

A

33. If a pharmacist dispenses cephalexin 250 mg capsules for the prescription below, what directions should be provided to the patient?

Rx

Cephalexin capsules 500 mg

Sig; 1 cap tid, 10 days

a. 2 caps 3x a day for 10 days

b. 3 caps 2x a day for 5 days

c. 2 caps 4x a day for 8 days

d. 3 caps once a day for 15 days

e. 2 caps 2x a day for 14 days

D

34. Spironolactone tablets are available in 25 mg strength, but a drug orders comes for 150 mg dose. How many tablets should be dispensed to last for 5 days?

a. 6

b. 12

c. 20

d. 30

e. 25

A

35. Calculate the (w/w) of coal tar in the finished product when 8 grams of coal tar is mixed with 120 grams of a 4% coal tar ointment.

a.10

b. 15

c. 20

d. 30

e. 25

D

36. If a 10 mL vial of insulin contains 200 units of insulin per milliliter, and a patient is required to receive 20 units twice daily, how many days will the product last the patient?

a. 20 days

b. 30 days

c. 35 days

d. 50 days

e. 45 days

B

37. A patients receives 30 mL of heparin every hour. If there are 40 units in each milliliter, how many units does the patient receive in 24 hours?

a.30, 200

b.28, 000

c. 12,440

d. 21,880

e. 14, 250

A

38. How many mL of a 1:500 v/v solution of methyl salicylate in alcohol can be made from 100 mL of 5 % v/v solution?

a. 2 500

b. 250

c. 5000

d. 1500

e. 3500

C

39. Calculate the IV flow rate for 500 mL D5W to run for 8 hours. The drop factor is 60 gtt/mL.

a. 70 gtts/min

b. 65 gtts/min

c. 63 gtts/min

d. 54 gtts/min

e. 72 gtts/min

A

40. If a vial of gentamycin contains 80 mg of drug in 2 mL, how many mcg of the drug are present in 0.02 mL

a. 800

b. 350

c.26

d. 655

e. 260

B

41. Atenolol is available in strength of 50 mg. If a prescription is written for 100 mg daily for three weeks as directed, how many tablets should be dispensed?

a. 20

b. 42

c. 21

d. 60

e.45

A

42. If Lactulose Syrup USP contains 10 g lactulose in 15 mL of the syrup, how many mL would provide the equivalent of 1.33 g of lactulose?

a. 2

b. 5

c. 10

d. 6

e. 4

A

43. In the calibration of a medical dropper, 2 mL of a pediatric drop solution was found to give 48 drops. If it is desired to administer 0.3 mL of the medication to a baby, approximately how many drops should be given?

a. 1

b. 3

c. 5

d. 8

e. 2

C

44. If an injectable solution contains 25 mcg of a drug substance in each 0.5 mL, how many mL will be required to provide a patient with 0.25 mg of the drug substance?

a. 15 mL

b. 10 mL

c. 5 mL

d. 1 mL

e. 20 mL

B

45. A certain elixir contains 0.325 g of the active ingredient per teaspoonful. At PhP 15.35 per lb, what is the cost (PhP) of the active ingredient needed to make one gallon of the elixir?

a. 6.41

b. 8.32

c. 24.06

d. 12.05

e. 9.36

A

46. If a 500 mL of ferric chloride solution weighs 650 g, what is its specific gravity?

a. 1.3

b. 0.7692

c. 1.45

d. 0.8451

e. 0.93

C

47. What is the density of a metal, 10 mL of which weighs 5450 mg?

a. 1.106

b. 0.670

c. 0.545

d. 10.5

e. 0.626

B

48. Calculate the specific volume of a syrup if 20 mL of it weighs 35 grams.

a. 1.75

b. 0.57

c. 1.86

d. 0.72

e. 0.76

A

49. What is the specific volume of sulphuric acid having a specific gravity of 1.826?

a. 0.548

b. 1.800

c. 0.431

d. 2.135

e. 0.673

B

50. What is the weight of 3.5 liters of alcohol having a specific gravity of 0.835?

a. 4.19 g

b. 2922.5

c. 2.92

d. 3102 g

e.454.3

C

51. How many grams would 1 pint of HCl weigh (sp. gr. 1.16)?

a. 345

b. 675

c. 549

d. 980

e. 560

A

52. What is the volume (in millimeters) of 2 kg of sulfuric acid with a specific gravity of 1.83?

a. 1093

b. 2095

c. 1205

d.1830

e.1003

B

53. If 500 mL of mineral oil is used to prepare a liter of mineral oil emulsion, how many grams of oil having a specific gravity of 0.87 would be used in the preparation of 1 gallon of emulsion?

a. 1780.1

b. 1646.5

c. 245.30

d. 1100.4

e. 1546.5

A

54. If 200 mg of propylhexedrine, a liquid having a specific gravity of 0.85, are used in a single nasal inhaler, how many millimeters of drug would be used in the manufacturing of 1000 inhalers?

a. 294

b. 308

c. 78

d. 402

e. 113

B

55. The inhalant dose of amyl nitrate is 0.25 mL, express the dose in minims.

a. 3.50

b. 4.06

c. 2.55

d. 0.88

e. 3.33

C

56. Given a solution of potassium permanganate prepared by dissolving twenty 0.2 g tablets in enough purified water to make two liters of resulting solution, what is the percentage strength of the solution?

a. 2.0 %

b. 4.0%

c. 0.2 %

d. 0.4%

e. 20.0%

A

57. In problem number 56, what is the ratio strength of KMnO4 solution?

a. 1:500

b. 1 :50

c. 1:250

d. 1: 20

e. 1:350

B

58. Express a patient's uric acid level of 6.0 mg/dL in terms of mg%.

a. 12

b. 6

c.0.6

d. 60

e. 16

A

59. If a 10 mL serum ampule is determined to contain 9 mg of glucose, express the concentration of glucose as mg%.

a. 90

b. 9

c. 18

d. 6

e. 0.9

D

60. What is the proof strength of a 40% alcohol?

a. 40

b. 60

c. 75

d. 80

e. 65

A

61. How many proof gallons does 20 wine gallons of a 15% v/v alcohol measure?

a. 6

b. 12

c. 3

d.20

e. 4

A

62. A glucometer shows that a patient's blood serum contains 135mg% glucose. Express this value in % w/v.

a. 0.135%

b. 1.35%

c. 0.27%

d. 13.5%

e. 3.15%

B

63. The fluoride concentration in drinking water is 0.5 ppm. Express this concentration in percent.

a. 0.005%

b. 0.00005%

c. 5%

d. 0.5 %

e.0.05%

C

64. If 600 mg of sodium chloride is dissolved in enough water to make three pints of NaCl solution, what is its concentration in % w/v?

a. 6%

b. 4%

c. 0.04%

d. 0.6%

e. 40%

A

65. What is the concentration of 0.04% (w/v) NaCl solution in ratio strength?

a. 1:2500

b. 1:166.67

c. 1:250

d. 1:400

e. 1: 225

A

66. What is the % w/w concentration of a 10% w/v cough syrup having a specific gravity of 1.120?

a. 8.93%

b. 11.20%

c. 12.50%

d. 7.15%

e. 9.85%

D

67. If a commercially available insulin preparation contains 2 ppm of proinsulin, how many grams of pro insulin would be contained in a 10 mL vial of insulin?

a. 0.00003

b. 0.004

c. 0.0007

d. 0.0002

e. 0.0006

C

68. Express the concentration of aromatic water in a ratio strength prepared by mixing 2 mL of aromatic oil in 450 mL distilled water.

a. 1:200

b. 1:312

c. 1: 227

d. 1:225

e. 1: 335

69. No question so verse for the day: "Dismiss all anxiety from your minds. Present your needs to God in every form of prayer and in petitions full of gratitude. Then God's own peace, which is beyond all understanding, will stand guard over your hearts and minds, in Christ Jesus."

A

70. Calculate the ratio strength of a sulfur ointment which contains two oz. of sulfur in thirty kilograms of ointment.

a. 1:1058

b. 1: 2030

c. 1: 3065

d. 1: 1150

e. 1: 1008

D

71. What is the percent strength of a 1:2000 potassium chloride solution?

a. 0.5

b. 1.8

c. 20

d. 0.05

e. 2.25

C

72. Calculate the weight in grams of two pints of syrup if its specific gravity is 0.975.

a. 970.26 g

b. 498.10 g

c. 922.35 g

d. 670.05 g

e. 899. 45 g

A

73. If five gallons of lotion contains one pound of talc, what is the percentage strength?

a. 2.4 %

b. 6.7%

c. 8.3 %

d. 10.5 %

e. 3.6%

B

74. What is the % w/v concentration of a solution made by mixing 35 g of main ingredients in 500 g of vehicle (sp. gr. 1. 2000)?

a. 1.25%

b. 7.75%

c. 16.2%

d. 8.4 %

e. 8.3 %

C

75. How many proof gallons are contained in 8 wine gallons of 75% (v/v) alcohol?

a. 20

b. 16

c. 12

d. 10

e. 15

D

76. A pharmaceutical manufacturer has 4500 gallons of 95% (v/v) alcohol. How many proof gallons are represented by this quantity?

a. 8050

b. 9250

c. 1450

d. 8550

e. 8250

A

77. The cost of 100 antacid tablets is PhP 68.50. What should be the selling price per hundred tablets to yield a 40% gross profit on the selling price?

a. 114

b. 210

c. 75

d. 88

e. 107

B

78. A bottle of (30's ) of analgesic tablet sold at PhP 75.00, thereby yielding a gross profit of 30% on the cost. What was the cost of the bottle of tablets?

a. 62.35

b. 57.70

c.68.50

d. 52.00

D

79. A prescription item costs a pharmacist PhP 45.00. Upon mark up of 35% on the cost plus a professional fee of PhP 30.00, what would be the price of the dispensed prescription?

a. 85.50

b. 92.25

c. 78.50

d. 90.75

e. 88.50

D

80. How many chloramphenicol capsules, each 250 mg are needed to provide 25 mg per kg per day for 1 week for a person weighing 175 lbs?

a. 43

b.38

c. 65

d. 56

e. 72

A

81. How many grams of sodium bicarbonate (MW= 84g/mole) should be used in preparing a liter of solution which is to contain 8 mEq of sodium bicarbonate in each 10 mL?

a. 67.2 g

b. 57.1 g

c. 73 g

d. 90 g

e. 52.4 g

A

82. How many grams of KCl (MW=74.54 g/mole) should be used in making a liter of solution containing 5 mEq of potassium per mL?

a. 372.7 g

b. 186.35 g

c. 435 g

d. 74.54 g

e. 433.3 g

C

83. Ether has a specific gravity of 0.72. How many milliliters will 60 grams measure?

a. 72

b. 43

c. 83

d. 96

e. 91

B

84. What bis the % w/w of a 75% preparation ( sp. gr. 1.085)?

a. 78

b. 69

c. 81

d. 62

e. 74

B

85. The patient is to take 1 teaspoonful of medication bid for 1 week. How many mL of the medication should the patient buy?

a. 60 mL

b. 70 mL

c. 120 mL

d. 150 mL

e. 80 mL

C

86. How many 2-fluid ounce bottles of a cough syrup can be obtained from one gallon of the cough syrup?

a. 50

b. 45

c. 64

d. 27

e. 56

B

87. From the following Ipecac Syrup, calculate the amount of Ipecac needed to prepare enough syrup to fill one hundred 15-mL prescription bottles:

Ipecac fluidextract 70 mL

Glycerin 100 mL

Syrup qs 1000 mL

a. 100

b. 105

c. 90

d. 120

e. 80

A

88. In what portion should 10% and 20% coal tar ointments be mixed to prepare a 5% ointment?

a. 3 parts/5parts

b. 5 parts/3 parts

c. 2 parts/ 6 parts

d. 1 part/ 3 parts

e. 5 parts/ 2 parts

A

89. What is the percentage strength of a 1: 10,000 potassium permanganate solution?

a. 0.01%

b. 1.10%

c. 20%

d. 0.5%

e. 10.0%

C

90. Calculate the ratio strength of a mixture prepared by mixing 2 oz of ZnO in one kilogram white petrolatum.

a. 1:500

b. 1: 35.78

c. 1: 18.62

d. 1: 23.97

e. 1:36.78

A

91. How many liters of a 95% sulfuric acid having a specific gravity of 1.82 should be used in preparing three liters of 10% sulfuric acid?

a. 0.17

b. 2.1

c. 0.32

d. 0.54

e. 0.22

D

92. What is the strength of sodium chloride solution obtained by evaporating 550 grams of a 12% solution to a final weight of 150 grams?

a. 63%

b. 38%

c. 21%

d. 34%

e. 57%

D

93. How many millilitres of a 50% w/v solution should be mixed with 2175 mL of a 10% w/v solution to make a 20% w/v solution?

a. 800 mL

b.615 mL

c.415 mL

d.725 mL

e. 650 mL

D

94. Calculate the number of mL of water needed to be added to a mixture of 700 mL of 55% v/v alcoholic solution and enough 20% v/v alcoholic solution to make 1000 mL if the final solution is to be 40% alcoholic solution.

a. 75 mL

b. 300 mL

c. 55 mL

d. 225 mL

e. 125 mL

B

95. If a dose of 1/600 gr is prescribed, its equivalent dose in microgram is:

a. 10

b.100

c.120

d. 60

e.80

A

96. A household measure of 1 wineglass is equivalent to:

a. 2 fluidounces

b. 4 fluidounces

c. 8 fluid drams

d. 4 fluid drams

e. 8 fluidounces

C

97. How many teaspoonfuls would be prescribed in each dose of an elixir if 6 fluid ounces contained 36 doses?

a. 4

b. 2

c. 1

d. 5

e. 3

A

98. If three pounds of a substance would be used in preparing 2000 tablets, how many milligrams are represented in each tablet?

a. 681

b. 725

c. 850

d. 1250

e. 632

B

99. If the dose of the drug is 1/16 grains, how many doses are contained in two drams?

a. 2045

b. 1920

c. 1560

d. 980

e. 1430

B

100. How many mEq of Na+ are in 200 mL NSS (MW= 58.5)?

a. 15.4

b. 30.8

c. 58.5

d. 9.0

e. 45.2