F&E Anemia 1

General Anemia - Hb threshold for Men

< 130 g/L (13 g/dL).

General Anemia - Hb threshold for Non-pregnant women

< 120 g/L (12 g/dL).

General Anemia - Hb threshold for Pregnant women

< 110 g/L (11 g/dL).

General Anemia - Global Burden

1.9 billion (24% of global population).

General Anemia - High risk groups burden

30-40% of women (15-49y) and young children (6-59 mo).

Middle East Anemia - Contributing factors for Iron deficiency

dietary patterns and increased heavy menstrual bleeding rates.

Middle East Anemia - Common Hemoglobinopathies

beta-thalassemia and sickle cell.

Middle East Anemia - Screening Programs aim

Premarital and antenatal screening aims to reduce transmission of thalassemia and sickle cell disease.

Iron Deficiency Anemia - Microcytic cause status

The commonest microcytic cause.

Iron Deficiency Anemia - Pattern confirmation

microcytic, hypochromic anemia.

Iron Deficiency Anemia - Iron studies to order

serum ferritin, serum iron, TIBC/transferrin saturation.

Iron Deficiency Anemia - Causes to find

Dietary, menorrhagia, GI blood loss, malabsorption.

Iron Deficiency Anemia - Occult malignancy investigation in men/postmenopausal women

Colonoscopy with or without upper endoscopy.

Iron Deficiency Anemia - First line treatment

Oral iron.

Iron Deficiency Anemia - Oral iron preparations

Ferrous sulfate/fumarate/gluconate.

Iron Deficiency Anemia - Oral iron every-other-day benefit

improves fractional absorption, decreases GI upset.

Iron Deficiency Anemia - Oral iron absorption enhancer

Take with vitamin C.

Iron Deficiency Anemia - Things to avoid with oral iron

tea, coffee, dairy, calcium, PPIs.

Iron Deficiency Anemia - Oral iron side effects

nausea, constipation, dark stools.

Iron Deficiency Anemia - Reassess Hb timing

2-4 weeks.

Iron Deficiency Anemia - Treatment continuation duration

Continue Rx 3m after Hb normalize to replenish store.