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why is an animal’s form not a perfect design?
natural selection can only act on what is already there
mechanisms by which existing structures arise from previous structures (evolutionary connection)
structures are going to be restricted physically due to its evolution
ex. giraffe’s long laryngeal nerve
anatomy
study of form of an organism’s structure
physiology
study of function of those structures
emergent properties
novel properties that were not present at the preceding level of the hierarchy of life
arise as a result of the structural and functional organization of each level’s component parts and the interaction among those parts
example of emergent properties
a single cell
muscle cell - to contract, and strands of proteins that perform that function are precisely aligned (each cell is branched and connected to other cells in a way that ensures coordinated contractions of the heart)
tissue (an integrated group of similar cells that performs a similar function)
the cells are specialized, and their structure enables them to perform a specific task
muscle tissue - cellular structure allows for coordinated contraction
organ (made up of two or more types of tissues that together performs a specific task)
heart - made up of muscle, nervous, epithelial, and connective tissue (heart’s ability to pump blood is resulted from the coordinated contraction)
organ system (multiple organs that together performs one or more vital body functions)
circulatory system - made up of the heart, blood and blood vessels, arteries, veins, and capillaries
organism (each organ system is specialized for certain tasks and all functioning together as an integrated, coordinated unit)
giraffe - systems cannot function without other systems and takes the coordination of several organ systems and emergent properties for life
tissues
an integrated group of similar cells that perform a common function and combine to form organs
4 main categories of tissues
epithelial tissue
connective tissue
muscle tissue
nervous tissue
extracellular matrix
one side of an epithelium is attached to a dense mat consisting of fibrous proteins and sticky polysaccharides
apical surface
one side that faces the outside of an organ or the inside of a tube or passageway
epithelial tissue
sheets of closely packed cells that cover the body surface and line the internal organs and cavities
tightly knit cells form a protective barrier and, in some cases, a surface for exchange with the fluid or air on the other side
*named according to
the number of cell layers they have
shape of cells on their apical surface
*the structure of each type fits its function
simple epithelium
single layer of cells
stratified epithelium
multiple layers
squamous
flat cells (like fried eggs)
cuboidal
cubed cells (like dice)
has large amounts of cytoplasm (absorbtion)
columnar
column-shaped cells (like bricks on the end)
has large amounts of cytoplasm (absorbtion)
simple squamous epithelium
thin and leaky
suitable for exchanging materials by diffusion (lines capillaries and air sacs of lungs)
simple cuboidal epithelium
tube in kidney, found in thyroid and salivary glands
simple columnar epithelium
lines intestines where it absorbs nutrients
stratified squamous epithelium
lines the esophagus, outer skin, mouth
regenerates rapidly
new cells move to apical surface as old cells die off
connective tissue
consist of a sparse population of cells scattered throughout a matrix
binds and supports other tissues
matrix
consists of a web of fibers embedded in a liquid, jelly, or solid
loose connective tissue
binds epithelia to underlying tissues and holds organs in place
matrix is a loose weave of fibers in a watery fluid
fibrous connective tissue
forms tendons (muscles to bone) and ligaments (bones to joints)
matrix of densely packed collagen fibers (maximizes its strength)
adipose tissue
stores fat in large, closely packed adipose cells
sparse matrix of loose fibers and fluid
cartilage
forms a string but flexible skeletal material (surrounds ends of bones; making it shock-absorbant)
matrix consists of collagen fibers embedded in a rubbery material
bone
provides shape and support for body (contains living cells — grows as you grow and mends when broken)
matrix of collagen fivers embedded in a hard mineral substance made of calcium, magnesium, and phosphate (makes bone strong and not brittle)
blood
transports substances throughout the body (functions differently)
extensive extracellular matrix is a liquid called plasma (water, salts, dissolved protiens)
suspended in plasma are red blood cells, white blood cells (fights against infections), and platelets (for clotting)
muscle tissue
the most abundant tissue in nearly all animals
functions in movement
consists of long cells called muscle fibers (contains many molecules of contractive proteins)
skeletal muscle
attached to bones by tendons and is responsive for voluntary movements of the body
arrangement of contractive units along the length of skeletal muscle fibers gives the cell a striped or striated appearance
cardiac muscle
forms the contractive tissue of the heart (involuntary control)
is striated but branched, interconnecting at specialized junctions that rapidly relay the signal to contract cell to cell during a heart beat
smooth muscle
involuntary body activities and found in the walls of the digestive trait, arteries, and other internal organs
has a lack of striations (hence the name) and contract slowly than skeletal muscle but can sustain contractions for longer periods of time
nervous tissue
forms a communication network by sensing stimuli and rapidly transmitting information
found in the brain and spinal cord, and nerves that transmits signals throughout the body
neuron (nerve cell)
structural and functional unit of nervous tissue
unquiely specialized to conduct electrical nerve impulses
dendrites — receives nerve impulses from other neurons (looks like roots or branches)
axons — transmits signals (looks like pathways)
cell body — necleus and orgenelles (center of neuron)
organ
made up of tissues
represents a higher level of structure than the tissues composing it and perform functions none of the individual tissues can carry out alone (emerge from coordinated interactions of tissues)
each tissue in the organ performs a specific function and can be organized into layers in some organs
the small intestine
lined by a columnar epithelium which includes connective tissues that contain blood vessels, and has two layers of smooth muscle that helps propel food (surrounded by another layer of connective tissue and epithelial tiddye)
the inner surface has many finger-like projections that increase the surface area for absorbing (villi and micro-villi)
organ transplants
hard to come by (lists are based by emergence and proximity)
compatibility is a major issue too
bio engineers are seeking ways to repair or replace damaged tissues or organs by 3-D printing
3-D printing organs and tissues
to create a layer of cells to resemble the structure of tissues and organs
however, they lack the correctly organized nerves, blood vessels, and other tissue and structures that would make them viable and functional in human bodies
scaffold
inner framework
integrity of the tissue or organ
ex. connective tissue matrix of a heart
new tissues and organs are being grown on a scaffold of connective tissue from donated organs
seeded with stem cells
stem cells
unspecialized cells that contain the genetic information to become specialized cells of the tissue or organ
organ systems
made up of organs
work together to perform life functions
the ability to carry out life’s functions is a result of the emergent properties stemming from the organization, interaction, and coordination of all the body’s organ systems working together
circulatory system
delivers oxygen and nutrients to body cells and transports carbon dioxide to the lungs and metabolic wastes to the kidneys
heart, blood vessels
respiratory system
exchanges gases with the environment, supplying blood with oxygen and disposing of carbon dioxide
nasal cavity, larynx, trachea, lungs, pharynx, bronchus
integumentary system
protects against physical injury, infection, excessive heat or cold, and drying out
skin, hair, nails
skeletal system
supports the body, protect organs like the brain and lungs, and provides the framework for muscle movement
bones, cartilage
muscular system
moves body, maintains posture, and produces heat
skeletal muscles
urinary system
removes waste products from the blood and excretes urine while also regulating the chemical makeup, pH, and water balance of the blood
kidneys, ureter, urinary bladder, urethra
digestive system
ingests and digests food, absorbs nutrients, and eliminates undigested materials
mouth, esophagus, liver, stomach, small and large intestines, anus
endocrine system
secretes hormones that regulates body activities, thus maintaining an internal steady state called homeostasis
hypothalamus, pituitary gland, thyroid gland, parathyroid gland, thymus, adrenal gland, pancreas, testis (male), ovary (female)
lymphatic system
returns excess body fluid to the circulatory system and functions as part of the immune system
lymph nodes, thymus, spleen, appendix, bone marrow, lymphatic vessels
immune system
defends against infections and cancer
lymph nodes, thymus, spleen, appendix, bone marrow, lymphatic vessels
nervous system
coordinates body activities by detecting stimuli, integrating information, and directing responses
brain, sense organs, spinal cord, nerves
reproductive system
produces gametes and sex hormones (female system supports a developing embryo and produces milk)
female: oviduct, ovary, uterus, vagina
male: seminal vesicles, prostate gland, vas deferens, penis, urethra, testis
skin
consists of two layers
epidermis
dermis
epidermis
a stratified squamous epithelium with many layers of flat cells
rapid cell division at the base of the epidermis served to replenish skin cells
fills with a protein keratin and releases oils
dermis
the inner layer of skin which consists of a fairly dense connective tissue with many elastic and collagen fibers (thinning of this layer results in wrinkled, sagging skin in older people)
contains hair follicles, oil, sweat glands, muscles, nerves, and blood vessels
hypodermis
layer of adipose tissue beneath the skin
site where vaccines and drugs are injected
vitamin D
required for absorbing calcium
folic acid
vitamin vital for fetal development
skin pigmentation and melanin
northern areas have lighter skinned people to get enough levels of both vitamins
southern areas have darker skinned people to avoid sunlight degrading folic acid while getting a healthy level of vitamin D
hair
flexible shaft of flexible, keratin-filled dead cells, which were produced by a hair follicle
oil glands lubricate the hair, condition the surrounding skin, and inhabit the growth of bacteria
wrapped in nerve endings
insulation of land mammals
muscles is responsible for raising hair (goose-bumps)
nails
protective coverings composed of keratin
well-designed experiments
examining one variable at a time, including randomized controls, and controlling for bias in data interpretation
control groups
individuals who were not treated but used for comparison
without it, we do not know the effects of that one particular variable (examining on one variable — ex. laser therapy)
should control all aspects and factors that could influence that controlled variable
*to determine the effectiveness and affects of that variable
open system
organisms which exchanges matter and energy with its surroundings
ex. humans take in water, food, and oxygen, and in exchange, they dispose of carbon dioxide, urinate, defecate, sweat, and radiate heat
*key idea: surface area to volume ratio
external exchange
body cells exchange materials directly with the environment
simple organisms (each cell in the body is close to the external environment — cells in small and flat organisms)
flattening (thin, flat body plan)
ex. parasitic tapeworm
internal exchange
an extensively branched or folded surface is a evolutionary adaptation that provides efficient exchange with the environment
increasing surface area to volume ratio
complex animals have specialized internal structures that increase surface area (act as exchange surfaces)
folding
creation of multiple layers or projections in tissues or organs to maximize the surface area relative to the volume
folded surfaces are internal protected by the integumentary system (25x larger surface area than skin in humans)
branching
the formation of multiple, interconnected pathways or structures in biological systems that enhance the distribution and exchange of materials
interstitial fluid
body cells are bathed in this fluid
this is where exchange takes place
direct exchange does not occur between blood and cells of tissues/organs but through this fluid
why do animals regulate their internal environment?
conditions often fluctuate widely in the external envrionemnt, by homeostatic mechanisms regulate internal conditions (smaller changes in an animal’s internal envrionment)
external envrionment
surrounds the animal
internal environment
where cells actually live
the interstitial fluid that fills the paces around cells
body maintains salt & water balance and body temperature (temperature has to be in a range in which the body and proteins can function properly for life)
homeostatis
a steady state (dynamic)
birds and mammals have control systems that keep body temperatures -and other factors - within a narrow range, despite large changes in the external environment
negative feedback
any control mechanism that reduces or reverses a change in the internal environment (bring back to the set point) — homeostasis depends on negative feedback
ex. regulating levels of glucose and temperature
positive feedback
any control mechanism that amplifies a change (bring away from set point)
ex. forming blood clots, producing contractions to push a baby out
hypothalamus
part of brain that regulates activities such as food intake, sleep, heart rate, hormone levels, and body temperature (maintains homeostasis)
responds to variations from the set point by switching on and off mechanisms