Neurobiology - Lecture 12: Taste

Part of Exam 3

Cranial Nerve Pneumonic:

On Old Olympus’ towering top, a Finn and German Vended Some Hops.

1. Olfactory
2. Optic
3. Occulomotor
4. Trochlear
5. Trigeminal
6. Abducens
7. Facial
8. Auditory-Vestibular
9. Glossopharyngeal
10. Vagus
11. Spinal Accessory
12. Hypoglossal

Type 1 Taste Cells

Supporting Cells

Salty Taste

Type 2 Taste Cells

Receptor Cells

Sweet, Bitter, and Umami Taste

Type 3 Taste Cells

Presynaptic Cells

Sour Taste

Spicy Taste

TRPV1 Pain Cells

Flavor

The influence of smell on taste

Sweet Taste

GCPRs; T1R2 & T1R3

Deletion affects non-caloric sweeteners but not complex polysaccharides.

Umami Taste

GCPRs; T1R1 & T1R3

Bitter Taste

GCPRs; T2R

Salty Taste

Ion Channel Receptors; Epithelial Sodium Channel (ENaC) & TRPV1

Sour Taste

Presynaptic Ion Channel; PKD2L1

Fat Taste

Fatty Acid Transporter CD36 in Lingual Papillae

Cranial Nerves Involved in Taste

CN-7 Facial Nerve

CN-9 Glossopharyngeal

CN-10 Vagus

CN-7 Facial Nerve

Carries info from anterior portion of tongue

CN-9 Glossopharyngeal

Carries info from posterior of tongue

CN-10 Vagus Nerve

Fibers from epiglottis (throat)

Nucleus of the Solitary Tract

CN-7, Cn-9, and CN-10

Aspartame is toxic to neurons in the _____.

Arcuate Nucleus

Cue Potentiated Feeding (CPF) influences __ and __ signaling

Ghrelin

Melanin-Concentrating Hormone (MCH)

Melanin-Concentrating Hormone (MCH)

An orexigenic peptide that signals to dopaminergic reward areas of the brain. Released from the LH.