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Arteries/arterioles function
Carry blood away from heart to capillaries
Capillaries function
Exchange of substances between tissues and blood
What color is oxygenated blood
Red
Vein/venule function
Carry blood to heart
What do blood vessels need
Oxygen/nutrients, bigger ones have own blood supply
What has lowest BP in whole body
Veins/venules
Inner layer of blood vessel name
Tunica intima (made of simple squamous epithelium)
Middle layer of blood vessel name
Tunica media (made of smooth muscle)
Name for outer layer of blood vessel
Tunica adventitia (connective tissue)
Middle layer function
Controls BP in arterioles
Largest artery in body and location
aorta (in heart)
What do capillaries do
Joins arterioles to venules
What substances are exchanged in capillaries
Oxygen, carbon dioxide, nutrients, wastes
Are all capillary beds open at same time
Never
Arteriovenous shunt
Allows capillaries to be bypassed
What closes off capillaries
Precapillary sphincter
Are veins stiff or elastic
Elastic; can stretch/expand to hold more blood
What is maximum % of blood in venous side of circulation at any one time
70%
Function of veins’ valves
Prevent backflow of blood
How do valves prevent backflow
Skeletal muscle action squeezes blood upward through valves
Largest veins
Vena cavae
Two types of vena cavae
Superior and inferior
How many chambers does the heart have
4 chambers
What are the 2 upper chambers called
Atria
What do 2 upper atrias do
Receiving chamber for blood from body/lungs
Name of two lower chambers
2 lower ventricles
What do ventricles do
Pump blood back into body/lungs
What is a septum
Separates each pair of chambers
Why does septum separate?
To keep oxygenated and deoxygenated blood separate. Right atrium = deoxygenated, left atrium = oxygenated
What is major portion of heart wall
Myocardium-cardiac muscle
what are inner surfaces of the heart wall lined with
Endocardium
Outer surfaces of heart wall are lined with)
Epicardium
what kind of tissue is endocardium
Epithelial
What kind of tissue is epicardium
Connective tissue
How many heart valves per chamber
One valve per chamber
What are heart valves called
Atrioventricular valves
Where are atrioventricular valves located
Between atrium and valve on each side
Where is mitral valve located
Between left atrium and left ventricle
Where is tricuspid valve located
Between right atrium and right ventricle
what are semi lunar valves
Aortic and pulmonary valve
Aortic valve location
Between left ventricle and aorta
Pulmonary valve location
Between right ventricle and pulmonary artery
What do all valves in heart do
Control blood flow through the heart
What do superior/inferior vena cavae do
Bring oxygen-lacking blood to right atrium
how is de-oxygenated blood oxygenated
Blood flows: superior/inferior VC → right atrium → tricuspid valve → right ventricle → pulmonary valve → pulmonary artery → lungs → pulmonary veins → left atrium → mitral valve → left ventricle →aortic valve → body.
Which side is pulmonary pump on
Right side
What does pulmonary pump do
Pump deoxygenated blood to pulmonary circuit/lungs
Which side is systemic pump
Left side
What does systemic pump do
Pumps oxygenated blood out to systemic circulation
What type of blood pressure is required for ventricle pumps to work
Higher BP
How long is cardiac cycle
0.8 seconds
How does each heartbeat occur
Both atria contract together, then both ventricles contract together. NEVER AT SAME TIME
Systole definition
Contraction of heart muscle
Diastole definition
Relaxation of heart muscle
Normal HR
60-80 BPM
What produces “lub dup” heart sounds
Turbulence/tissue vibration as valves close
When does “lub” sound occur
When Atrioventricular valves close
When do “dups” occur
When semilunar valves close
What are heart murmurs
Leaky valves producing abnormal heart sounds
What is autorhymicity
Cardiac muscle contracting w/out neural stimulation
what are nodal tissues
2 areas in heart that have both muscular/nervous properties
What do nodal tissues do
Generate action potentials to cause contractions
What does SA node do
Produces electricity
What is normal conduction pathway
SA node in right atrium starts impulse → spreads through atria → AV node delays and sends it down AV bundle → through septum → Purkinje fibers spread it through ventricles.
What happens if AV fails
Ventricles can contract alone (20-40 BPM)
How to have extrinsic control of heartbeat
Parasympathetic stimulation decreases HR, then sympathetic increases HR and contractility.
Can hormones control heart rate
Yes
What two chemicals cause increased HR
Epinephrine and norepinephrine
When do epinephrine and norepinephrine increased HR occur
Exercise, fight/flight
What does electrocardiogram do
measures electrical activity of heart
What is P-wave
Atrial depolarization (contraction)
What is QRS complex
Ventricular depolarization
What is T-wave
ventricular depolarization -relaxing
Tachycardia
Pulse at rest over 100 BPM
Bradycardia
Pulse at rest under 60 BPM
Sinostrial block
Signal from SA node doesn’t reach atria, no p-wave
Atrioventricular block
Signal gets delayed too much going to ventricles, P-R interval too long
Ventricular fibrillation
Erratic quivering of ventricles, constant small movements but no pumping occurs. Lethal
Cardiac arrest
Flatline
Atrial fibrillation
No meaningful P-wave, atria isn’t fully contracting. Not lethal because ventricles still contract
Is sinoatrial block lethal
No; 70% of blood still goes through
Pulmonary circuit locations
Right ventricle pumps deoxygenated blood to lungs via pulmonary arteries → gas exchange in alveolar capillaries →oxygenated blood returns to left atrium via pulmonary veins.
Systemic circuit locations
Left ventricle pumps oxygenated blood into aorta → systemic arteries → capillaries (O2 dropped, CO picked up) - venules/veins → superior/inferior vena cava → right atrium.
What does coronary circulation do
Supply heart muscle
what are coronary arteries
First branches off aorta, located on heart surface, distribute blood to heart muscle
Where is blood collected in coronary circulation
Collected in venules, then opened into coronary veins
What atrium do coronary veins enter into
Right atrium
Hepatic portal system cleaning process
Carries nutrient-rich blood from digestive tract to liver via hepatic portal vein. Liver absorbs nutrients, detoxifies blood, and sends clean blood to inferior vena cava via hepatic veins.
Where is highest blood flow
Aorta
Where is lowest blood flow
Vena cavae
What is blood pressure
Pressure of blood against vessel walls
What has highest pressure
Systolic pressure
What has lowest pressure
Diatomic pressure
What does blood pressure account for
Flow through arteries and arterioles
When does blood pressure decrease
As blood flows throughout your body, spreads out
What is the normal blood pressure
110/70
What does 110/70 represent in BP
Systolic/diastolic
Function of papillary muscle
To help close valves