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Evidence-based care
Care that is based on EBP, supported by scientific evidence, clinical expertise and client values
Evidence-based practice
A practice that is supported by scientific evidence, clinical expertise and client values. The conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients
Knowledge
An accepted body of facts or ideas that is acquired through the use of the senses, reasons or through research methods
Retrospective longitudinal cohort design
A type of study conducted over a long period, looking at a group of people in the past
Research
Focused systematic enquiry aimed at generating new knowledge
Advanced search
Setting specific parameters for results (year/author/title/study type)
Boolean operators
AND, OR, NOT: used to expand or exclude keywords in a search (provides more focus)
Search string
List of words or phrases, when combined are used to search for a specific piece of information in database)
Primary research
An original piece of research from a single study
Secondary research
Research that has examined multiple primary research papers (summarised)
Truncation
A searching technique used when searching databases in which a word ending is replaced by
a symbol — an asterisk (*), a question mark (?) or a dollar sign ($) — to enable the search to include
all possible endings of the word.
Wildcards
A searching technique used when searching databases in which a letter in a word is replaced
by a symbol — an asterisk (*), a question mark (?) or a dollar sign ($) — to enable the search to
include alternate spellings of the word.
Clinical significance
The relevance or importance of the results/findings to real-life practice
Grey literature
Information published by organisations other than commercial publishers, such as government reports, company brochures, conference papers, policy statements and academics theses and dissertations
Heard immunity
Indirect protection from infection due to a high level of immunity in the community
Homogeneity
The comparability of results of one study with that of another
Meta-analysis
Statistical procedure for combining results from existing quantitative studies with measured outcomes, effectively increasing sample size and precision
Meta-synthesis
Synthesis of a number of qualitative studies examining the same phenomenon
Peer review
Evaluation of a paper by experts in that field, usually done blind where the reviewer does not know who has written the paper to avoid bias
Primary paper
An article written by researchers who carried out the study it describes, it is new research with the original findings also known as original research or empirical research
Publication bias
When published research is not representative of all completed studies in that area, leading to false conclusions as to the entire body of evidence, this is often skewed towards positive results
Secondary paper
A paper that reviews several original/primary papers written by other people, no new research is carried out by these authors
Statistical significance
The likelihood that a result is produced by more than chance, usually accepted to be expressed through a p-value of less than 0.05 (e.g. more than 95% probability that the effect resulted from the intervention)
Anonymity
A person’s information is anonymous, if the information cannot identify the person. Name, date of birth or address has been removed.
Autonomy
Freedom to determine one’s own actions
Beneificance
Acting to benefit humankind
Confidentiality
Maintenance of privileged information
Declaration of Helsinki
First historical document outlining ethical principles to govern research, first agreed to in 1964
HREC
Human Research Ethics Committee
Justice
Obligation to treat fairly
NHMRC
(National Health and Medical Research Council) the peak funding and policy-making body for medical research in Australia
Non-maleficence
Avoiding or minimising harm
Privacy
The person’s right to choose and control what happens to personal information
Deductive
Going from general to specific
Inductive
Going from specific to general
Inter-rater reliability
When 2 or more researchers assess the data and results and give consistent estimates of the same phenomenon
Progressive focusing
The ability to review the research at various stages and adjust accordingly if required to improve on the study
Reflexivity
Examining oneself as the researcher as well as the research relationship. Making the research process and researcher a focus of inquiry
Saturation
Little or no new data is generated from the participants, and it is believed that the sample size is adequate
Triangulation
Improves validity of a study because it cross-validates data through verifying the research results through 2 or more sources, typically through the application or combination of different research methods, attempting to answer the same questions
Dependent variable
For intervention studies, the outcome measures expected to be affected by the intervention (independent) variable.
Descriptive research
Observational studies describing and optionally comparing the characteristics or responses of a sample.
Diagnostic accuracy study
A research design evaluating how well a clinical diagnostic or assessment procedure can identify the presence or absence of a health condition in a sample
Epidemiological research
The scientific study of causes and other factors affecting the occurrence illnesses, injuries, survival or recovery among populations and groups within a population
Experimental design
An intervention study involving at least one treatment group and a control or placebo group, so the effect on outcomes with and without the intervention can be compared
Independent variable
For intervention studies, the intervention or the treatment expected to affect the outcome (dependent) variable
Intervention study
Research where the researchers deliberately do something with participants with the intention of causing a change
Level of measurement
How quantitative information is recorded, according to whether only group membership (nominal scale) or ranking (ordinal scale) is identified, or whether quantities or amounts are directly measured (continuous scales). Continuous scales (interval and especially ratio) are considered more informative levels of measurement than categorical (nominal or ordinal) scales
Observational study
Research where the researchers do not intervene to bring about a change but instead observe and measure events as they happen naturally
PICO
A way of listing the clinical population, intervention (treatment), comparison or control conditions and measured outcomes for an experiment; useful for identifying search terms for intervention studies
Reliability
In measurement, the consistency and repeatability of measurement scores over time, measurement equipment and people doing the measuring
Systematic review
Secondary research evidence that answers a focused clinical question through a structured and rigorous synthesis of original, primary studies chosen with strict and transparent inclusion and exclusion criteria
Validity
In measurement, the accuracy of a measurement, whether a measurement system measures what it’s supposed to measure, and only what it’s supposed to measure, which depends in part on reliability
Variable
Anything measurable, either categorically or continuously, and can differ from one observation to another, such as among different individuals, groups of people, or across time
Allocation bias
Systematic differences in clinical trial groups and affecting results beyond treatments
Bias
Systematic, consistent error in results or conclusions from evidence; renders the evidence invalid or likely to be misinterpreted where the bias is concealed
Clinical practice guidelines
Document providing evidence-based recommendation for the clinical management of patients with a specific, known health condition
Clinical question
An inquiry about clinical practice, ideally answered from research evidence
Database
An organised list that can be searched by computer. In evidence-based practice, a catalogue of research evidence retrievable according to design of study, topic, clinical population or health condition, authorship, year of publication or other criteria relevant to the clinical question, the quality and accessibility of the evidence
Evidence
Information from research that may guide practice if that evidence is valid for the clinical scenario
Evidence-based practitioners
Health professionals who use recent, high-quality, relevant evidence from research in combination with professional judgement and the patient’s preferences and values to inform healthcare practice and policy decisions
GRADE system
A method for evaluating the quality of evidence used to develop recommendations informing clinical practice guidelines
Hierarchy
An ordered list, from highest (better) to lowest (not so good)
Levels of evidence
A list of study designs matched to clinical questions, and ranked in order of potential bias
Placebo
An intervention resembling a real treatment but without any expected therapeutic benefit.
Primary evidence
Evidence from original studies collecting data from new research published for the first time
Secondary evidence
Evidence compiled from existing, already available research results
Ontology
Definition
3 types
Quantitative
Qualitative
Mixed methods
What exists and what is the reality?
Realism
Relativism
Both (pragmatism-mixed)
Quantitative, singular reality
Qualitative, multiple reality
Mixed methods, singular and multiple realities
Epistemology
Definition
3 types
Quantitative
Qualitative
Mixed methods
Ways of knowing to generate understanding of the world
What do we know and how do we know it?
empiricism/objectivism (quant), constructivism (qual), pragmatic stance (mixed methods)
Quantitative, impartial and objective
Qualitative, closeness and subjective
Mixed methods, practicality
Methodology
Definition
Quantitative
Qualitative
Mixed methods
A system of methods, principles and rules for that subject area
How do we find out?
Quantitative, deductive
Qualitative, inductive
Mixed methods, multiple
Methods
Definition
Tools/techniques used to collect evidence/data
What specific procedures or tools do we use to find out?
Ethnography
The art and science of describing a group or culture of interest
Requires blending of methodological techniques particularly participant observation
Ethnography
Passive observation
Systematic watching of behaviours and conversations in natural occurring settings — known to be the study of cultures and people
In passive observation, the researcher is meant to observe the culture from the point of view of the participant.
Ethnography
Participant observation
Observation in which the researcher also occupies a role or part in the setting in addition to observing.
In participant observation, the researcher is meant to observe the culture from the point of view of the participant — essentially be embedded in the culture of observation
Phenomenology
A school of thought that emphasises a focus on people's subjective experiences and interpretations of the world
In the context of their illness, disability or health system experience
Involves studying a small number of subjects through extensive and prolonged engagement to develop patterns and relationships of meaning
Case studies
Used to look at individuals, a small group of participants, or a group as a whole. This approach begins with a clear definition of the case being researched and the researcher explores the people, behaviours, etc. based on the defined question of the research. The result of a case study is typically a report providing great detail about the case that was researched
Grounded theory
Grounded theory refers to a inductive or informant led process of generating theory from data
Considered as ground-up or bottom-up processing
Involves immersing yourself in the participants words and developing literal understanding generating meaningful codes and theory
Semi-structured interview
Face-to-face, telephone or skype conversation with participant(s) with the purpose of exploring issues or topics in detail. Uses a broad list of questions or topics (known as a topic guide)
Unstructured/narrative interview
Interview undertaken in a less structured fashion, with the purpose of getting a long story from the interviewee (typically a life story or the story of how an illness has unfolded over time). The interviewer holds back from prompting except to say 'tell me more'.
Focus groups
Method of group interview that explicitly includes and uses the group interaction to generate data
Discourse analysis
Detailed study of the words, phrases and formats used in particular social contexts (includes the study of naturally occurring talk as well as written materials such as policy documents or minutes of meetings)
Inductive thematics
Like grounded theory it is a rigorous method for identifying, analysing and reporting patterns/themes within data
Flexible approach that can be conducted independent of theory and epistemology
Or applied across a range of theoretical and epistemological approaches
There it can be essentialist/realist where it reports experiences, meanings and the reality of participants
Or constructionist, examines the ways in which events, realities, meanings and experiences operate within society
Helps to generate new understanding as opposed to developing theory
Narrative design
Weaves together a sequence of events from 1 or 2 individuals to form a cohesive story
By listening to what people have to say about their lives we can better understand how phenomena or experiences are embedded in the context of an entire life and give meaning
The way people conduct, interpret and understand themselves, others and events is by storying and re storying and by telling and further listening to their own and each other's
Detection bias
Differences in how the treatment and control groups are assessed or measured
Performance bias
Events other than the intended treatment happen during the experiment
Attrition bias
Some types of participants leave the study, more so in one group than another, setting up unwanted differences between groups in the background characteristics of the participants
Measurement bias
Outcomes are measured inaccurately
Time lag bias
Delays in publication prevent the research from being found by practitioners or reviewers in time for their review
Duplicated publication bias
The same results from the same studies are repeatedly published, suggesting there’s more evidence than there really is
Outcome reporting bias
Mainly desirable or large expected results or statistically significant results get published, even though other results are equally valid and informative; another type of publication bias
Citation bias
If a study is cited a lot by many other authors, reviewers are more likely to find that research compared with studies that are rarely cited or not cited at all
Database inclusion bias
Studies are much more easily found if they are available from online databases
Language bias
A preference among reviewers for studies published in the language they understand, commonly but not always English
Reviewer's’ personal biases
Reviews may unfairly exclude an article because they don’t like the topic or the results, even though the results are valid and relevant