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Mucosa
Innermost G.I. tract lining with epithelial layer.
Epithelium
Stratified squamous in mouth; simple columnar in stomach.
Submucosa
Areolar connective tissue, highly vascular for nutrition.
Muscularis externa
Thick double layer of smooth muscle for motility.
Peristalsis
Movement of food along G.I. tract.
Segmentation
Churning of food in one location.
Serosa
Thick fibrous tissue providing structure and protection.
Autonomic Nervous System
Controls G.I. tract function via intrinsic and extrinsic pathways.
Intrinsic Nervous System
Nerve plexus regulating G.I. tract functions locally.
Extrinsic Nervous System
Long pathways from brainstem regulating digestion.
Parasympathetic Nervous System
Stimulates digestion and salivary secretion.
Sympathetic Nervous System
Suppresses digestion and salivary secretion.
Peritoneum
Double-walled serous membrane surrounding G.I. tract.
Salivary Glands
Three pairs producing saliva for digestion.
Saliva
99.5% water; contains ions and digestive enzymes.
Deglutition
Swallowing process, initially voluntary then involuntary.
Rugae
Interior stomach folds increasing surface area.
Parietal Cells
Secrete HCl and intrinsic factor for vitamin B12.
Chief Cells
Secrete pepsinogen and gastric lipases for digestion.
Enteroendocrine Cells
Secrete hormones, including gastrin for digestion.
Chyme
Liquid food mixture entering the duodenum.
HCl Formation
Stimulated by acetylcholine, gastrin, and histamine receptors.
Pancreas
Endocrine and exocrine functions; secretes digestive enzymes.
Hepatocytes
Liver cells that synthesize bile and regenerate.
Bile
Fluid that emulsifies fats, secreted into duodenum.
Liver Functions
Includes metabolism, bile synthesis, and vitamin storage.