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Somites are derived from?
Paraxial mesoderm
The two parts of somite differentiation?
Sclerotome and dermomytome
The mesenchyme is formed from what?
The sclerotome
What is the process of bone development called?
Osteogenesis
What are the two types of bone formation
Membranous (flat bones that develop in the mesenchyme) or endochondral (limb bones)
When does cartilage formation begin in the mesenchyme?
Week 5
What are the three types of cartilage
Hyaline, fibrocartilage, elastic cartilage
Where does intramembranous ossification occur?
Within a membranous sheath and produces osseous tissue without prior cartilage formation
Where does the 1° center of ossification appear?
Diaphysis
What does the perichondrium become?
Periosteum
Where does the lengthening of bones occur at?
Diaphyseal-epiphyseal junction
Ossification of limb bones begins at?
End of embryonic period
What are important minerals for bone development
Calcium and phosphorus
When do joints begin to resemble adult joints?
By end of week 8
What are the three classifications of joints?
Fibrous, cartilaginous, and synovial
What are the four parts of the axial skeleton
Cranium/skull, vertebral column, ribs, sternum
When does development of the vertebral column begin?
Week 4-5
When is the cartilaginous stage?
Week 6
When is the bony stage
Week 7
When does ossification begin and end
Begins week 7 and ends by 25th year
When do bony halves fuse
3-5 years of life
What signaling pathways are involved in the patterning of vertebral column?
NOTCH signaling pathways
Where do the ribs develop from
Mesenchymal costal process
During the embryonic period ribs are ____ and during the fetal period ___
Cartilaginous, ossification begins
number of pairs of true, false, and floating ribs
7, 5, 2
T/F all ossification centers, including xiphoid, appear before birth
False, all EXCEPT xiphoid, appear before birth
What are the two subdivisions of the cranium
Neurocranium and viscerocranium