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What is a hypothesis?
A. A method for producing scientific results
B. A statement or question to be tested by a research study
C. A complete description of what will happen to the animals
D. The final results that will be published by the principal investigator
B. A statement or question to be tested by a research study
What is an Experimental Group?
Animals that receive a test substance or treatment
What is a Hypothesis?
A clear theory to explain the research problem or question
What is a Control Group?
Animals that do not receive a test substance or treatment
What is the IACUC Protocol?
A document that clearly defines and explains the use of animals in a study
What is a Variable?
Any factor that can influence a study
What is Applied Research?
Studies that try to answer a specific scientific question
True or False:
Animals may not be ordered and no work can begin in the study until the IACUC approves the protocol.
True
List five non-experimental variables that can affect laboratory animal research results.
Mix-ups in strains of animals
Improper animal identification
Errors in weighing or medicating animals
Incorrect recording of data
Variations in room temperature, lighting, diet, bedding, or cage type
What is an animal model?
Animals worked with in research studies
Why is it important that the control group be treated exactly the same as the experimental group?
Investigators can compare and observe differences or changes in the animals and determine if it was a result of the treatment
List four items that an animal use protocol could include.
Why a particular species or strain is needed
Complete description of how animals will be used
Timeline of all procedures conducted
Describe when and how they will be euthanized
List three administrative bodies that may have input on the IACUC protocol review.
Environmental Health and Safety
Radiation Safety
Biosafety
Some laboratory animals naturally acquire a disease that is similar to the same condition in humans. What are these animals called?
A. Natural research subjects
B. Fortuitous animals
C. Biosimilar types
D. Spontaneous animal models
D. Spontaneous animal models
What is Basic Research?
A study exploring normal or abnormal of major organ systems
What is Applied Research?
A study to improve treatment of a specific disease
What is a Safety Evaluation?
A study to make sure a chemical or compound is safe in humans
What are New Drug Studies?
A study to develop a new drug therapy for a disease
