Random (the rest) of Top Drugs

Acetylcysteine (brand)

Acetadote

Acetadote (generic)

Acetylcysteine

Acetylcysteine (dosing)

300mg/kg total dose administered as a 21 hours IV infusion regimen consisting of 3 doses. First load over 1 hours, second over 4 hours, third over 16 hours

Acetadote (dosing)

300mg/kg total dose administered as a 21 hour IV infusion regimen consisting of 3 doses. First load over 1 hour, second over 4 hours, third over 16 hours

Acetylcysteine (indication)

acetaminophen overdose

Acetadote (indication)

acetaminophen overdose

Acetylcysteine/Acetadote (MOA)

hepatoprotective restoring hepatic glutathione and enhancing the nontoxic sulfate conjugation of acetaminophen

Acyclovir (brand)

Zovirax

Zovirax (generic)

Acyclovir

Acyclovir (dosing)

200mg orally every 4 hours for 5 doses/day for 10 days

Zovirax (dosing)

200mg orally every 4 hours for 5 doses/day for 10 days

Acyclovir/Zovirax (MOA)

inhibits DNA synthesis and viral replication by competing with deoxyguanosine triphosphate for viral DNA polymerase and being incorporated into viral DNA

Acyclovir (indication)

antiviral

Zovirax (indication)

antiviral

Alendronate (brand)

Fosamax

Fosmax (generic)

Alendronate

Alendronate (dosing)

10mg orally once daily OR 70mg once weekly

Fosamax (dosing)

10mg orally once daily OR 70mg po once weekly

Alendronate/Fosamax (indication)

osteoporosis

Alendronate/Fosamax (MOA)

adheres to sites of bone reabsorption, inhibiting osteoclast activity. Normal bone is formed on top of alendronate, which is then incorporated into the bone matrix

Allopurinol (brand)

Zyloprim

Zyloprim (generic)

Allopurinol

Allopurinol (dosing)

200-300mg po qd

Zyloprim (dosing)

200-300mg po qd

Allopurinol/Zyloprim (indication)

gout

Allopurinol/Zyloprim (MOA)

competitive inhibition of xanthine oxidase which prevents the conversion of hypoxanthine to xanthine to uric acid

Alteplase (brand)

Activase

Activase (generic)

Alteplase

Alteplase (indication)

Acute ischemic stroke (AIS)

Activase (indication)

acute ischemic stroke

Alteplase (dosing)

load with 0.09mg/kg IV over 1 minute, followed by 0.81mg/kg continuous infusion over 60 minutes (max 90mg)

Activase (dosing)

load with 0.09mg/kg IV over 1 minute, followed by 0.81mg/kg continuous infusion over 60 minutes (max 90mg)

Alteplase/Activase (MOA)

Initiates local fibrinolysis by binding to fibrin in the thrombus and converts entrapped plasminogen to plasmin

Amiodarone (brand)

Cordarone, Pacerone, Nexterone

Cordarone, Pacerone, Nexterone (generic)

Amiodarone

Amiodarone (indication)

Arrhythmia

Cordarone, Pacerone, Nexterone (indication)

Arrhythmia

Amiodarone (dosing)

200-400mg po qd

Pacerone, Cordarone, Nexterone (dosing)

200-400mg po qd

Amiodarone// Cordarone, Nexterone, Pacerone (MOA)

Class III antiarrhythmic that lengthens cardiac action potential by prolonging intranodal conduction and refractoriness of the AV node

Amiodarone// Cordarone, Nexterone, Pacerone (BBW)

• Use only intended for life-threatening arrhythmias due to risk of toxicity

• Pulmonary and hepatic toxicity may occur during therapy

• May exacerbate arrhythmias and therefore should be initiated where continuous ECG and cardiac resuscitation are available

Anastrozole (brand)

Arimidex

Arimidex (generic)

Anastrozole

Anastrozole (indication)

Breast cancer

Arimidex (indication)

breast cancer

Anastrozole (dosing)

1mg po qd

Arimidex (dosing)

1mg po qd

Anastrozole/Arimidex (MOA)

Selective non-steroidal aromatase inhibitor which prevents the conversion of androstenedione to estrone and testosterone to estradiol. This decreases tumor mass or delays tumor progression.

Benzonatate (Brand)

Tessalon

Tessalon (generic)

Benzonatate

Benzonatate (indication)

antitussive

Tessalon (indication)

Antitussive

Benzonatate (dosing)

100mg po TID prn

Tessalon (dosing)

100mg po TID prn

Benzonatate/Tessalon (MOA)

Topical anesthetic activity in respiratory stretch receptors

Bimatoprost (ophthalmic) (brand)

Lumigan, Latisse

Lumina, Latisse (generic)

Bimatoprost

Bimatoprost (dosing)

1 drop into affected eye(s) once daily in the evening

Lumina, Latisse (dosing)

1 drop into affected eye(s) once daily in the evening

Bimatoprost (indication)

glaucoma

Lumigan, Latisse (Indication)

glaucoma

Bimatoprost//Lumigan, Latisse (MOA)

Synthetic prostaglandin analog which reduces intraocular pressure by increasing the outflow of the aqueous humor

Brimonidine Tartrate (brand)

Alphagan-P

Alphagan-P (generic)

Brimonidine Tartrate

Brimonidine Tartrate (indication)

Glaucoma

Alphagan-P (indication)

Glaucoma

Brimonidine Tartrate (dosing)

1 drop into affected eye(s) TID 8 hours apart

Alphagan-P (dosing)

1 drop into affected eye(s) TID 8 hours apart

Brimonidine Tartrate/ Alphagan-P (MOA)

Alpha 2 adrenergic agonist which reduced production of aqueous humor and increased outflow

Butalbital, APAP, and caffeine (indication)

tension headache

Fioricet (indication)

tension headache

Butalbital, APAP, and caffeine (brand)

Fioricet

Fioricet (generic)

Butalbital, APAP, and caffeine

Butalbital, APAP, and caffeine (dosing)

• Capsule- 50mg/300mg/40mg

• Tablet- 50mg/325mg/40mg

  • Dose- 1-2 capsule/tablet every 4 hours prn not to exceed 6 capsules/tablets per day

Fioricet (dosing)

• Capsule- 50mg/300mg/40mg

• Tablet- 50mg/325mg/40mg

  • Dose- 1-2 capsule/tablet every 4 hours prn not to exceed 6 capsules/tablets per day

Butalbital, APAP, and caffeine/ Fioricet (MOA)

• Butalbital—CNS depressant by activating inhibitory GABA receptor and inhibition of AMPA receptors

• Acetaminophen—Inhibits CNS prostaglandin synthesis and block pain impulse generation

• Caffeine—CNS stimulant by inhibition of phosphodiesterase increasing levels of c-AMP

Butalbital, APAP, and caffeine/ Fioricet (BBW)

APAP has been associated with liver failure typically at dosing exceeding 4,000mg/day

Carbidopa/Levodopa (brand)

Sinemet, CR, Rytary

Sinemet, CR, Rotary (generic)

Carbidopa/Levodopa

Carbidopa/Levodopa (dosing)

25/100mg po TID

Sinemet, CR, Rytary (dosing)

25/100mg po TID

Carbidopa/Levodopa//Sinemet, CR, Rotary (MOA)

Levodopa is a precursor to dopamine Carbidopa is a DOPA-decarboxylase inhibitor and prevents the breakdown of levodopa before it crosses the BBB, combined these increase the dopamine available to the CNS

Carisoprodol (brand)

Soma

Soma (generic)

Carisoprodol

Carisoprodol (indication)

pain relief of musculoskeletal conditions

Soma (indication)

paint relief of musculoskeletal conditions

Carisoprodol (dosing)

250-350mg po TID and at bedtime

Soma (dosing)

250-350mg po TID and at bedtime

Carisoprodol (controlled?)

CIV

Soma (controlled?)

CIV

Carisoprodol/Soma (MOA)

Central depressant resulting in musculoskeletal relaxation