Drug Abuse and Effects

Flashcards covering drug abuse, effects, and classifications.

Alcohol

The most commonly abused drug in the world, causing vast medical and societal costs.

Chronic use of PCP may lead to what irreversible symptom?

Schizophrenia-like psychosis

Dextromethorphan

An over-the-counter cough suppressant that can produce a dissociative state at high doses.

Which drugs are known as dissociative anesthetics because they cause a feeling of mind-body separation and act by use-dependent inhibition of NMDA glutamate receptors?

Phencyclidine (PCP) or Ketamine

Lysergic acid diethylamide (LSD)

A drug that activates 5-HT2A receptors in the prefrontal cortex, enhancing perception.

Cortical and thalamic circuits

The primary target of hallucinogens and dissociative anesthetics instead of the mesolimbic dopamine system.