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Recombinant Proteins and Peptides — Sheep

Epidermal Growth Factor (EGF) is used for chemical shearing, facilitating wool removal and reducing the labor-intensive manual shearing process.

Recombinant Proteins and Peptides — Horses

Equine Growth Hormone (eGH) is administered to decrease skeletal weaknesses, particularly in performance horses, and helps prevent leg injuries by promoting stronger bones.

Special Dosage Form Considerations with Recombinant Proteins and Peptides

Recombinant proteins and peptides require special formulation and delivery considerations because of their chemical and physical instability.

Recombinant Proteins and Peptides — Veterinary Applications

Used in cattle, pigs, sheep, and horses for purposes including improved feed conversion efficiency, milk production, leaner carcasses, chemical shearing, and reducing skeletal weaknesses.

Liquid or Semisolid Dosage Forms — Advanced Veterinary Dosage Forms

Advanced dosage forms include Controlled Internal Drug Release (CIDR) systems, liquid or semisolid parenteral products, intra-articular drugs, recombinant proteins and peptides, and vaccines.

Vaccines

Veterinary dosage forms used to provide protection against specific diseases.

Vaccine Formulation — Special Considerations

Vaccine formulation must consider the stability and biological activity of the vaccine components.

Vaccine Delivery

Vaccines may require specific dosage forms and administration routes to maintain effectiveness.

Liquid or Semisolid Parenteral Products

Products administered by injection that may be formulated as solutions, suspensions, emulsions, or lyophilized powders.

Intra-Articular Drugs

Drugs administered directly into a joint for targeted treatment of joint conditions.

Recombinant Proteins and Peptides — Instability

These compounds present formulation and delivery challenges because of their chemical and physical instability.

Dosage Form Development for Biotechnologically Engineered Products

Requires consideration of the unique properties of recombinant proteins and peptides to maintain efficacy and stability.

Veterinary Biotechnology Applications

Biotechnologically engineered products can be used to enhance productivity and manage specific health conditions in animals.

Cattle — bGH Application

Bovine Growth Hormone (bGH) is used to increase feed conversion efficiency and milk production and enhance overall productivity in dairy and beef cattle.

Pigs — pGH Application

Porcine Growth Hormone (pGH) is used to improve feed conversion efficiency and promote leaner carcasses.

Sheep — EGF Application

Epidermal Growth Factor (EGF) is used for chemical shearing to facilitate wool removal.

Horses — eGH Application

Equine Growth Hormone (eGH) is used to decrease skeletal weaknesses and help prevent leg injuries by promoting stronger bones.