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Functional group consisting of an oxygen atom bonded to a hydrogen atom (−OH), highly polar and capable of forming hydrogen bonds
Hydroxyl group
Nonpolar hydrocarbon functional group (−CH3) that affects gene expression and molecular shape
Methyl group
Acidic functional group (−COOH) that donates a hydrogen ion (H+) to become negatively charged (−COO−)
Carboxyl group
Basic functional group (−NH2) found in amino acids that accepts a hydrogen ion (H+) to become −NH3+
Amino group
Functional group (−SH) found in cysteine that forms disulfide bonds essential for protein tertiary structure
Sulfhydryl group
Negatively charged, highly polar group (−PO43−) located at the 5′ end of nucleotides
Phosphate group
Property of water that enables evaporative cooling through sweating
High heat of vaporization
Structural explanation for why solid ice floats on liquid water
Water expands upon freezing as hydrogen bonds lock molecules into a rigid, open crystalline lattice, making solid ice less dense than liquid water
Core principle of molecular biology detailing the flow of genetic information
Central Dogma (DNA→RNA→Protein)
Process of synthesizing mRNA from a DNA template strand
Transcription
Process of synthesizing a protein amino acid chain from mRNA
Translation
Three structural components of a DNA nucleotide
A nitrogenous base (A, T, C, or G), a deoxyribose sugar, and a phosphate group
Nitrogenous base present in RNA that replaces thymine (T)
Uracil (U)
Direction in which RNA polymerase reads the DNA template strand during transcription
3′ to 5′ direction
Direction in which mRNA is synthesized during transcription
5′ to 3′ direction
Primary translation start codon and the amino acid it encodes
AUG (codes for Methionine)
The three mRNA translation stop codons
UAA, UAG, and UGA
Cellular locations of transcription and translation in eukaryotic cells
Transcription occurs in the nucleus; translation occurs in the cytoplasm or on the rough endoplasmic reticulum
Primary role of tRNA during translation
Transports specific amino acids to the ribosome based on codon-anticodon pairing
Type of membrane transport moving substances against their concentration gradient requiring energy (ATP)
Active transport
Stoichiometry of ion movement performed by the sodium-potassium (Na+/K+) pump per cycle
Pumps 3Na+ ions out of the cell and 2K+ ions into the cell using one molecule of ATP
Mechanism of action by which tetrodotoxin (TTX) disrupts nerve impulse transmission
Blocks voltage-gated sodium (Na+) channels, interfering with action potentials