Pharmacodynamics

Pharmacodynamics

Pharmacodynamics

Pharmacodynamics 2

Receptor Protein

Receptor Protein 2

Ligands

Ligand

Drug affinity

Drug affinity

High affinity

Dose response relationships

Potency efficacy

Drug potency

Drug efficacy

Drug efficacy

Drug potency and efficancy

Morphine Buprenorphine

Ligand-receptor protein agonist

Partial agonists vs full agonists

Antagonists

reversible vs irreversible binding

revers vs irrevers

key points

Drug selectivity

Drug selectivity

drug specificity

Therapeutic index

Therapeutic window

index and window

upregulation

Downregulation

Drug tolerance

Mechanisms of drug tolerance

key points

Types of protein for drug action rice

receptors

Ligand

ionotropic receptors

metabotropic receptors

Kinase linked receptors 2 key parts

kinase linked receptors

Nuclear receptors

ion channels

carrier molecules transport

Enzymes

Drug as a substrate