The electrical potential of a cell when not actively conducting an action potential, typically around -70 mv.
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Threshold Potential
The critical level to which a membrane potential must be depolarized in order to initiate an action potential; typically around -55 mv.
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Depolarization
The process during an action potential where the membrane potential becomes less negative, usually leading to a positive peak around +10 mv.
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Repolarization
The process of restoring the cell membrane potential to a more negative value following depolarization.
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Overshoot
The phase in an action potential where the membrane potential goes beyond the resting membrane potential due to slow K+ channel closing.
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NA/K Pump
A mechanism that actively transports 3 Na+ ions out of the cell and 2 K+ ions into the cell, using ATP to maintain the electrochemical gradient.
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Glutamate
The primary excitatory neurotransmitter in the nervous system.
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GABA (Gamma-Aminobutyric Acid)
The primary inhibitory neurotransmitter in the nervous system.
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Chemoreceptors
Sensory receptors that transduce chemical substances into biological signals, sensitive to changes in the chemical environment.
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Photoreceptors
Sensory receptors that transduce light into biological signals, critical for vision.
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Mechanoreceptors
Receptors that respond to mechanical pressure or distortion.
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Proprioceptors
Sensory receptors located in muscles, tendons, and joints that provide information about body position and movement.
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Rods
Photoreceptors sensitive to light, responsible for scotopic (dim light) vision.
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Cones
Photoreceptors responsible for photopic (bright light) vision, color vision, and visual acuity.
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Golgi Tendon Organs (GTO)
Proprioceptors that sense muscle tension and protect against excessive force.
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Muscle Spindles
Proprioceptors that detect changes in muscle length and provide information about muscle stretch.
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Alpha Motor Neurons
Neurons that directly innervate extrafusal muscle fibers to cause contraction.
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Gamma Motor Neurons
Neurons that innervate intrafusal fibers in muscle spindles to adjust sensitivity.
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Phototransduction Cascade
The process through which light photons absorbed by opsins in photoreceptors result in changes to cellular signaling pathways.
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Thermoreceptors
Sensory receptors that respond to changes in temperature.
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Baroreceptors
Mechanoreceptors that sense pressure changes in blood vessels.
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Pacinian Corpuscles
Mechanoreceptors that respond to deep pressure and vibration.
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Meissner's Corpuscles
Mechanoreceptors that detect light touch and vibration.
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Ruffini Endings
Mechanoreceptors that respond to stretch and sustained pressure.
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Photopsin
The type of opsin protein found in cone photoreceptors, involved in color vision.
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Rhodepsin
The type of opsin protein found in rod photoreceptors, involved in low light vision.
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Alpha-Gamma Coactivation Hypothesis
The theory that during voluntary muscle contractions, both alpha and gamma motor neurons are activated simultaneously to maintain muscle spindle sensitivity.
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Nociceptors
Sensory receptors that respond to potentially damaging stimuli, signaling pain.
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Homeostasis Regulation
The process by which the body maintains stable internal conditions, including blood pressure and chemical concentrations.