Liver and Pancreas testing | Quizlet

Where is ALT found

cytoplasm of hepatocytes

Where is AST found

Mitochondria of cells

Where is ALP found

Hepatocytes, renal tubules and interstitial epithelial cells.

Horses normal AST level

205-5550u/l

Cattle normal AST level

58-100 u/l

Dog normal AST level

1-37 u/l

Cat normal AST level

6-44 u/l

Increase in AST (200)

Cirrhosis

Inflammation of pancreas

hemolysis

Increase in AST (200-400)

Skeletal muscle disease

chronic hepatitis

surgical procedures

parasites

Increase in AST (400-4000)

Myocardial infaction

viral hepatitis

toxic liver damage.

Cancer.

Increase in ALT seen when:

Liver cirrhosis

Pancreas inflammation

hemolysis

viral hepatitis

toxic liver damage

Increase in ALP is seen in:

Rickets/ osteomalacia

Cancer

Vit D deficiency

Calcium and Phosphorus deficiency

Hyperpaarthyroidism

Cholestasis

Kidney disease

Decrease in ALP is seen in:

Hypophosphatenia

Cretinism

Ascorbic acid deficiency

Achrondroplasia.

Increase in GGT:

Cholestasis

Damage to hepatocytes

Diseases with infiltration of the liver parenchyma.

LDH Where is it found

All cells of body including RBC

When can an increase of LDH occur

Hemolytic anemia

Proteolytic pancreas enzymes.

Trypsin, chrymotrypsin, carboxypeptidase, elastase

Lipolytic enzymes

Lipase, phospholipase, esterase

Glycolytic enzymes

amylase

Nucleolytic enzymes

Ribonuclease