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Which of the following is not parental route?
Hair follicle
Which of the following is NOT a component of invasiveness?
Coagulation
Which of the following components are part of invasiveness?
All of the above (capsule, cell wall, hyaluronidase)
__________ are very specific
Exotoxins
Which of the following are endotoxins?
Lipopolysaccharides
What is the rate of Microbial death
They are killed at a constant rate
What is an E Test?
a manual in vitro diagnostic device used by laboratories to determine the MIC (answer will say something about the strips used in the device)
What is the most effective form of chlorine?
Hypochlorous acid
What is the concentration of ethanol?
70%
If you use too much antibacterial soap, what happens?
The normal flora will be killed and you will become more susceptible to catch microbes
What is not evidence of Koch's Postulates?
Some diseases have poorly understood etiology/some diseases are noncommunicable
What is a sporadic disease called?
Index case
What period shows signs and symptoms?
Prodromal period
Diseases that occur primarily in wild and domestic animals and can be transmitted to humans are called
Zoonoses
What type of transmission of disease is it called when a person sneezes?
Droplet transmission
You can get pathogens from nonliving things called:
Fomites
Is the passive transport of the pathogens on the insect's feet or other body parts:
Mechanical transmission
Biological transmission
an active process and is more complex; The arthropod bites an infected person or animal and ingests some of the infected blood
How can emerging disease come about?
all of the above
What does an epidemiologist do?
Collect and analyzes the occurrence of the disease
What is morbidity rate?
The number of people affected by a disease in a given period of time in relation to the total population
A change in body function that is felt by a patient as a result of a disease:
Symptom
_________ inhibits folic acid synthesis
Sulfonamides
what do sulfonamides have to do with therapeutic index (how it affects humans)?
The drugs are bacteriostatic and do not harm human cells because we take up folic acid from our diet rather than synthesize it
The organism that has a parasite living within it is the:
Host
The period with the least degree of symptoms is the ___________ period.
incubation
An infection that occurs in many nations is a/an ___________.
pandemic
A nosocomial infection is:
always acquired during the course of hospitalization
Which of the following is not reservoir of infection?
none of the above (a sick person, a healthy person, a sick animal, a hospital)
A/n _______________ carrier is an individual who harbors the infectious organism but is not ill.
healthy
The most frequently used portal of entry for pathogens is the
Mucous membranes of the respiratory tract
The LD50 is a
Lethal dose that will kill 50% of the test population
Endotoxins are:
part of the gram-negative cell wall
Lysozyme is an enzyme found in tears and __________________.
saliva
Which of the following organisms doesn't produce an exotoxin?
Salmonella typhi
Nonspecific resistance (innate immunity) is:
The body's defenses against any kind of pathogen
If we are healthy, we have a high level of _______ in our blood
Interferon
Which of the following statements is "true" about interferon?
interferon is an antiviral protein
Your ability to ward off disease is called:
immunity
Ultrasound kills by
cavitation
The killing of vegetative form of pathogenic microorganisms (usually on inanimate objects) is called
disinfection
The lowest temperature at which a microbial population is killed in a specified period of time is the
thermal death point (TDP)
Fractional exposure to any method is called
tyndallization
The disinfectant of choice for municipal water supplies is _______________.
chlorine
Which will require a longer time to kill?
a larger population of microorganisms
Which of the following is the best method for sterilization?
incineration
Tetracyclines are derived from:
Streptomyces
Mechanisms by which antibiotics kill or inhibit microbial growth are:
all of the above
Microbes commonly present in or on the body are called
normal flora
Penicillin become widely used because of the work of:
Fleming
PMN is another name for ___________________ cell.
neutrophil
The control center for fever development is located in the:
hypothalamus
The immune system normally discriminates between _______________ antigens
self and nonself
Most pathogens that gain access through the skin
enter through hair follicles and sweat ducts
Misuse of antibiotic resistances includes:
Using antibiotics in animal feed
The relationship between normal microbiota and the host in which at least one organism is dependent on the other
Symbiosis
The type of symbiotic relationship where one of the organisms benefits, and the other is unaffected
Commensalism
Disease thatoccurs occasionally in a population at irregular intervals
Sporadic disease
The resistance to the spread of a contagious disease within a population
Herd immunity
Denatures a toxin and makes it inactive; when it enters the body, the body will recognize it as a toxin but it will not cause damage
Toxoid
Neutrophils, basophils, and eosinophils are:
Granulocytes (phagocytosis)
Involves the membrane attack complex
Cytolysis
Immune adherence, promotes attachment of a phagocyte to a microbe
Opsonization
Causes cells to produce antiviral proteins that inhibit viral replication
IFN-alpha and IFN-beta
The best method to sterilize heat labile solutions:
membrane filtration
Chemical agents that is used for sterilization:
ethylene oxide
Substances used for surgical hand scrubs:
chlorhexidine
False statement regarding antimicrobial control agents:
alcohols effectively inactivate nonenveloped viruses by attacking lipids
A limitation of the autoclave
it cannot be used with heat labile materials
Application of heat to living cells can result in all of the following except:
decreased thermal death time
A disinfectant that acts by disrupting the plasma membrane
bisphenol
Oxidizing agents include:
chlorine, hydrogen peroxide, iodine, and ozone
Disinfection of water is not achieved by:
peracetic acid
Substance NOT effective against nonenveoled viruses:
alcohol
Method used to preserve food by slowing the metabolic processes of foodborne microbes:
freezing
Could be used to sterilize plastic petri plates in a plastic wrapper:
microwaves
Results in lethal damage to nucleic acids:
heat, radiation, and some chemicals
An iodophor is an:
iodine mixed with a surfactant
Ethylene oxide is a
sterilizing agent
Is NOT used to preserve food:
biguanides
What is NOT effective in destroying prions:
boiling
Which is not a method of food preservation:
microwaves
The preservation of beef jerky from microbial growth relies on which method of microbial control:
desiccation
If you were preparing nutrient agar at home and did not have an autoclave, what could you use to sterilize the nutrient agar:
pressure cooker @121 Celsius for 15 minutes
Bone and tendons for transplant are decontaminated by:
supercritical fluids
Most resistant to chemicalbiocides:
gram negative bacteria
All of the following factors contribute to hospital-acquired infections EXCEPT
None of the above
The following is true of quarternary ammonium compounds EXCEPT
they are effective when combined with soap
A transient microbiota differ from normal microbiota in that transient microbiota are:
present for a relatively short time
A commensal bacterium
may also be an opportunistic pathogen
The major significance of Robert Koch's work is that
microorganisms cause disease
Which of the following diseases is not spread by droplet infection
botulism
Which of following diseases are spread by droplet infection
all of the following (tuberculosis, measles, the common cold, diptheria)
Focal infection initially start out as
local infection
The rise in herd immunity amongst a population can directly attributed to
vaccinations
Which of the following is a reservoir of infection
all of the following (sick person, a healthy person, a sick animal, a hospital)
Which of the following are a communicable diseases
all of the following (malaria, AIDS, tuberculosis, typhoid fever)
Which of the following is NOT a communicable diseases
Tetanus
Which is a fomite
a hypodermic needle
Which of the following can contribute to postoperative infections
all of the following (using syringes more than once, normal microbiota on the operating room staff, errors in aseptic technique, antibiotic resistance)