T Cells

Flashcards about T cells.

Killer T Cells

Killer T cells; two types are cytotoxic T lymphocytes (CTL) and natural killer (NK) cells.

T Cells

Lymphocytes that mature in the thymus and become either CD4 positive or CD8 positive cells.

Helper T cells

Activate macrophages, induce inflammation, and help B cells and CD8 T cell response.

Cytotoxic T cells (CTL)

Lyses infected cells or cancer cells.

Innate Response

Cells that can establish in hours to days, while adaptive immunity takes days or weeks.

Secondary Lymphoid Organ

The primary site for T cell priming, either in the lymph node or in the spleen.

Naive T cells

Recognize cognate peptide presented by dendritic cells, then proliferate and differentiate.

Dendritic Cells

One of the most powerful antigen-presenting cells; presents the peptide to T cells.

Immunological Synapse

Enhances interaction between CD8 T cells and target cells, stabilizing the interaction.

Granulotoxin

Membrane-disrupting protein and enzymes that lead to apoptosis in target cells.

Perforin

Membrane disrupting protein that punches a hole on the membrane to allow entry of granzyme.

Fas Ligand

Expressed on activated CTL on the T cells, and the Fas expressed on target cells

Antibody-dependent cell-mediated cytotoxicity (ADCC)

Killer cells bind to antibody-coated cells through Fc receptors.