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Layers of kidney
cortex and medulla
Nephron
functional unit of kidney
ICF vs ECF
ICF 67%
ECF 33%
IF 80%
plasma 205
How does the kidney maintain homeostasis
excretion of waste
regulation of normal blood values (ionic composition/osmolarity, pH, volume, pressure)
production of calcitriol and erythropoietin
basic process of nephron
glomerular filtration
tubular reabsorption
tubular secretion
Where does most reabsorption occur
in the proximal convoluted tubules
Excretion equation
excretion = (filtration + secretion) - reabsorption
roles of antidiuretic hormone (vasopressin)
increases permeability of collecting duct
increase water reabsorption at kidneys
aldosterone function
inc. Na+ reabsorption and K+ excretion
inc. water absorption due to Na+
Quiet inspiration
decrease by 3 mmHg
diaphragm (move down) and external intercostals (contract)
Forced inspiration
decrease 20 mmHg
sternocleidomastoid, scalenes, and pectoralis minor (contract)
Quiet Expiration
increase by 3 mmHg
external intercostals and diaphragm (relax)
Forced expiration
increase by 30 mmHg
abdominal muscles and internal intercostals (contract)
Spirometer
measures amount of air breathed in
lung elasticity, airway resistance, and muscle strength
Tidal volume
air inhaled/exhaled during normal/quiet breath
inspiratory vs expiratory reserve volume
inspiratory: max volume of air inhaled after normal inhale
expiratory: max volume exhaled normally
Residual volume
vol. of air in lungs after max expiration
Vital capacity
max vol. exhaled after max inspiration
inspiratory reserve volume + tidal volume + expiratory reserve volume
inspiratory capacity
Inspiratory respiratory reserve + tidal volume
max air inhaled after normal exhale
functional residual capacity
expiratory reserve volume + residual volume
volume of air in lungs at end of normal exhale
Total lung capacity
IRV + TV + ERV + RV
Path of filtration
glomeruli
proximal convoluted tubule
Loop of Henle
distal convoluted tubule
collecting duct