Quiz 19 Urea Cycle

Glutamate is metabolically converted to α-ketoglutarate and NH4+ by a process described as:

oxidative deamination

In the urea cycle, ornithine transcarbamoylase catalyzes formation of _____ from _____ and another reactant

citrulline, ornithine

Urea synthesis in mammals takes place primarily in tissues of the:

liver

Alanine and pyruvate are interconverted by which enzyme?

alanine aminotransferase

Which reaction associated with the urea cycle occurs in the cytosol?

the synthesis of arginosuccinate

Deamination of MOST amino acids in the liver is accompanied by the conversion of:

a-ketoglutarate to glutamate.

What enzyme converts arginine into urea and ornithine?

arginase

In which pair of compounds is the second molecule produced by the deamination of the first molecule?

alanine and pyruvate, glutamine and glutamate, aspartic acid and oxaloacetate

Which cofactor is typically required in transamination reactions?

pyridoxal phosphate

Which statement is true regarding the conversion of arginine to ornithine in the urea cycle?

The enzyme catalyzing this reaction is a _________.

hydrolase