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histamine is a type
cytokine
plasma
mostly water, albumin ( a protein), electrolytes, hormones, plasma proteins (like coagulation factors and antibodies) and dissolved gases
serum *buffy coat”
platelets and leukocytes
microbiome is a layer of defense because
•compete with pathogens for nutrients
•block attachment to epithelium
•produce toxins to inhibit pathogen growth
innate
broadly specific
PAMP and DAMP
recognized by toll like receptors
cd4
•Act Directly through cytotoxic chemicals
humoral
memory b and plasma cells that make antibodies
CD8 receptor
•that interact with MHC I receptors on health cells to scan for viral particles that indicate “infected”
Microfilaments
motility- cell shape changes. used in contraction of muscle
intermediate filaments
cell stability (keep organelles in place)
microtubule
cell shape facilitate the movement of organelles and vacuoles. “roadmap” accumulation of tau protein(normally stabilize the microtubule in neurons) can tangle microtubule which disrupts the transmission of neurotransmitters
cytoplasm
everything between cell membrane and nucleus
1.inclusion: special to cell type ex:glycogen in muscle and liver
2.cytosol:water, protein, salt, sugar
3.organelles