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Compressed Gas Association (CGA)
Sets standards and safety guidelines for manufacturing, transporting, and storing compressed gases.
National Fire Protection Association (NFPA)
Creates standards for storage of flammable and oxidizing gases.
Department of Transportation (DOT)
Regulates cylinder construction, testing, and transportation.
Food and Drug Administration (FDA)
Sets purity standards for medical gases
Bureau of Medical Devices (BMD)
Provides standards and regulates medical devices.
Occupational Safety & Health Administration (OSHA)
Ensures safe working conditions for employees.
Flammable Gas Definition
Explosive when mixed with air or oxygen in the right proportions.
Non‑Flammable Gas Definition
Not easily ignited and does not burn rapidly if ignited.
Examples of Non‑Flammable Gases
Nitrogen (N₂), Carbon dioxide (CO₂), Helium (He).
Combustion Definition
Rapid chemical reaction with oxygen that releases heat.
Gases that Support Combustion
Oxygen, Nitric Oxide, Compressed Air, Nitrous Oxide, O₂/N₂, Heliox, O₂/CO₂.
Anesthetic Gases
Nitrous Oxide, Ethylene, Isoflurane.
Lab Gases
CO₂, Helium, Nitrogen, Carbon Monoxide (DLCO testing).
Therapy Gases
Medical Air, Oxygen, Heliox, O₂/CO₂, O₂/N₂.
CO₂ Characteristics
Colorless, odorless, 1.5× heavier than air, does not support combustion.
CO₂ Tank Color
Gray/Silver.
CO₂ Purity Requirement
FDA purity ≥ 99%.
Helium Characteristics
Very low density, odorless, tasteless, nonflammable, stable.
Helium Purity Requirement
FDA requires 99% purity.
Heliox Common Ratios
80/20, 70/30, 60/40.
Heliox Indications
Upper airway obstruction (croup, post‑extubation edema, epiglottitis), severe asthma, COPD exacerbation.
Why Heliox Works
Lower density improves airflow through narrowed passages.
Medical Air Characteristics
Colorless, odorless, density 1.29 g/L, filtered/purified atmospheric air.
Medical Air Purity Requirement
FDA purity 99%.
N₂O Characteristics
Colorless, sweet odor/taste, non‑flammable but supports combustion.
N₂O Uses
Analgesic, anxiolytic, anesthetic (dentistry, labor & delivery).
Oxygen Characteristics
Colorless, odorless, tasteless, transparent, nonflammable but supports combustion.
Oxygen Density
1.43 g/L (heavier than air).
Oxygen Purity Requirement
FDA purity ≥ 99%.
Nitric Oxide Characteristics
Colorless, toxic if overdosed, nonflammable but supports combustion.
Nitric Oxide Action
Potent vasodilator.
NO Indications
FDA‑approved for PPHN; used off‑label for adults.
DOT 3A Cylinder
Made from carbon steel.
DOT 3AA Cylinder
Heat‑treated steel alloy; stronger than 3A.
Meaning of “+” on Cylinder
Meaning of “*” on Cylinder*
Approved for 10‑year hydrostatic test interval.
Small Cylinder Connection Type
Yoke (PISS)
Large Cylinder Connection Type
Threaded valve (ASSS).
Oxygen
Green
CO2
Gray
Nitrous Oxide
Blue
Helium
Brown
Medical Air
Yellow
Heliox
Brown/Green
O2/CO2
Gray/Green
Service Pressure Definition
Pressure at 70°F when filled.
Full Tank Example
2000 psi + 10% = 2200 psi.
E‑Tank Conversion Factor
0.28
H‑Tank Conversion Factor
Why subtract 200 psi?
Safety buffer to avoid running out.
Minimum Capacity
≥ 13,000 cubic feet.
Liquid Oxygen Expansion Ratio
1 cu ft liquid = 860 cu ft gas.
Manifold System Definition
Multiple large cylinders grouped together at a fixed site.
Manifold Requirement
Must have backup system.
Working Pressure
Reduced to 50 psi.
Zone Valves Purpose
Shut off gas in case of leak or fire.
ASSS
Threaded, high‑pressure connections for large tanks.
DISS
Low‑pressure (<200 psi) threaded connectors with specific diameters.
PISS
Pin‑indexed system for small cylinders (AA–E).
Oxygen Pin Positions
2 & 5
Reducing Valve
Reduces gas pressure to usable level.
Flowmeter (Thorpe Tube)
Measures/regulates flow; range 0.25–15+ LPM.
Flow Restrictor
Fixed orifice delivering a specific flow at constant pressure.
Bourdon Gauge
Flowmeter used with adjustable high‑pressure regulator; reads flow based on pressure.
How to Clear Valve Outlet
Open and close valve quickly.
Never Use Oil Because…
Oil + oxygen = explosion risk.
How to Store Unsecured Tanks
Lay them on the floor.
Monitor PSI
Frequently check while in use.
Compression
Atmospheric air is compressed to high pressure
Cooling
Compressed air is cooled until it liquefies
Distillation
Nitrogen boils off first; oxygen remains as the heavier liquid
Collection
Purified liquid oxygen is stored and later vaporized for medical use