Dimenhydrinate (Dramamine) - antihistamines/anticholinergics -for Nausea

Flashcards covering key concepts about dimenhydrinate, its uses, reactions, administration, and precautions based on pharmacological guidelines.

What is the therapeutic use of dimenhydrinate?

• Anti-emesis, vertigo, motion sickness.

What are the common adverse drug reactions associated with dimenhydrinate?

• Sedation and

• Dry mouth, urinary retention, and constipation (anticholinergic effects)

What should be monitored in clients taking dimenhydrinate?

• Monitor clients when ambulating,

• Monitor for anticholinergic effects,

• Bowel elimination patterns, vital signs, and manifestations of anaphylaxis.

How should dimenhydrinate be administered?

• Orally, IM, or IV;

• Initial dose should be given 30 to 60 minutes before triggering activity.

• Subcu doses given before meals and at bedtime.

• Do NOT swallow chewable tablets

What client instructions should be provided for dimenhydrinate?

• Avoid driving or activities requiring mental alertness,

• Sit or lie down if drowsy,

• Change positions gradually,

• Increase fluid and fiber intake,

• Urinate every 4 hours, and

• Report changes in urinary elimination.

What are the contraindications for dimenhydrinate?

• Hypersensitivity,

• Angle-closure glaucoma, and

• Use in preterm or newborn infants.

What precautions should be taken when administering dimenhydrinate?

• Use caution in cases of hyperthyroidism, cardiovascular disease, hepatic disease,

• Pyloric obstruction, prostatic hypertrophy, older adults, and during pregnancy and lactation.

What interactions should be noted with dimenhydrinate?

• Other CNS depressants can increase its sedative effects, and

• MAO inhibitors can increase anticholinergic effects.