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Define diabetes mellitus and differentiate between types.
Diabetes mellitus: a condition in which the body struggles to metabolize glucose because of insufficient insulin or from a decreased response to it.
Type I DM: Congenital/unmodifiable, absolute lack of insulin, more frequent in childhood, must administer insulin (insulin-dependent)
Type II DM: acquired/modifiable, genetically-linked, usually adult-onset
Gestational: during/after pregnancy, complications include increased birth weight and preeclampsia, half of people develop T2DM later in life
Know the USPSTF criteria for screening for diabetes and prediabetes in an adult patient
USPSTF: screening for prediabetes/T2DM in adults 35-70 who have overweight/obesity (BMI>25)
Consider earlier screening for those with risk factors
In addition to weight: older age, family history, history of PCOS, dietary/lifestyle factors
Gestational diabetes: screen at 24 weeks or later (grade B)
Identify the risk of diabetes in pregnant people
increased risk of developing T2DM later in life for both mother and child
Obesity, sedentary lifestyle
Older age
Family history
Identify the risk of diabetes in children and adolescents
Increasing rates of obesity and sedentary behavior (plus usual risk factors)
Identify the risk of diabetes in the elderly
Age-related decreased insulin sensitivity
Increased abdominal fat and loss of muscle mass
Physical inactivity
Poor diet and nutritional deficiencies
Polypharmacy
Other comorbidities
What is the impact of DM on the heart?
Atherosclerosis leading to CAD
HTN
Increased risk of HF and MI
Must manage lipid levels, keep under certain ranges
Minimize glucose swings and control BP
What is the impact of DM on the brain?
infarcts/bleeds
Ischemic stroke
Cognitive decline and dementia
Diabetic neuropathy
Must manage blood pressure and lipid levels
Diabetes-related dementia
What is the impact of DM on the kidneys?
Glomerular damage, CKD
HTN/fluid retention
Monitor eGFR/labs, albumin if necessary
Glucose management necessary
Primary prevention for diabetes
Diet: Mediterranean, DASH, Diabetes focused Medical Nutrition Therapy (MNT)
active lifestyle
education
Secondary prevention for diabetes
Screenings (USAPTF recommendations)
Gestational diabetes: screen at 24 wks or later (grade B)
Prediabetes: Monitor for T2DM at least annually
Pre-symptomatic Type 1: monitor HgbA1C every 6 mo.
Monitor for central obesity/metabolic syndrome, activity levels, and sleep apnea
Tertiary prevention for diabetes
Continuous glucose monitor – especially for T1DM, Blood glucose meters
Insulin pump, smart insulin pens
Education: S/S of hyper+hypoglycemia, immediate care, and sustained control with meals
Foot exams to screen for peripheral neuropathy, education about how to prevent
Monitor lipid levels and BP to prevent end-organ damage
What are the primary ways to monitor and manage blood glucose?
Continuous glucose monitor
Insulin pump
Blood glucose meters
Smart insulin pens
What does a continuous glucose monitor do?
continuously measures and displays blood glucose levels in real-time, sensor just under skin
How does an insulin pump work?
delivers insulin continuously or in bolus doses, cannula inserted into skin
What are blood glucose meters?
portable device to measure blood glucose using finger stick method
How do smart insulin pens work?
automatically record insulin injection data (time, dose) and can connect to mobile apps to help manage diabetes, can help calculate appropriate dose
What education about DM should you provide?
S/S of hypoglycemia: sweating, tremors, pallor, sweating, irritability, dizziness
S/S of hyperglycemia: polyphagia, polydipsia, polyuria, lethargy, confusion
Immediate treatment of hypoglycemia: something to bring the blood sugar up – OJ, simple carbs
Sustained control: something to keep the sugar from rebounding down – peanut butter, complex carbs or protein
What does HbA1C (Hemoglobin A1C) measure and what is its disadvantage?
a blood test that measures the average blood glucose levels over the past 2-3 months by determining the percentage of hemoglobin that has glucose attached to it
An average HbA1C that is improved doesn’t necessarily mean the person kept their BG at a good level: it doesn’t catch the possible highs and lows
education about foot care in DM
Footwear: well-fitting, cushioned shoes and socks to prevent blisters and ulcers; avoid walking barefoot
Toenails: train straight across
Importance of keeping intact skin– daily foot inspection
Wash with lukewarm water and soap, dry thoroughly
Foot exam at least annually: includes inspection, pulses, and monofilament test
Discuss barriers to treatment adherence and methods to address them
Age: children or elderly
Tailor education and care to age group
Unable to make certain lifestyle changes (cost, time, education, access, motivation, cultural considerations)
Provide education
Set SMART goals
Culturally competent care
High cost of medications and equipment
Cost-saving programs
Community care
Metformin administration and side effects
generally the first line for T2DM
take same time every day, with food, increase water intake
Side effects: gastric issues – abdominal discomfort, diarrhea, loss of appetite
Insulin information and side effects
Administration: injection, can be automatic or manual
Pricing and storage considerations: store in fridge, expensive
Side effects: possible hypoglycemia
What are the risk factors, both modifiable and non-modifiable, for hypertension?
Modifiable: smoking, DM, dyslipidemia/high cholesterol, weight, sedentary lifestyle, excess alcohol, high fat and sodium diet
Non-modifiable: age, family hx, male sex, sleep apnea, psychosocial stress, CKD, low socioeconomic status
What are the values of normal, elevated, Stage 1, and Stage 2 hypertension?
Normal: SBP under 120 and DBP under 80
Elevated: SBP 120-129 and DBP under 80
Stage 1: SBP 130-139 and DBP 80-89
Stage 2: SBP 140+ and DBP 90+
Explain the physiologic effects of sustained chronic hypertension on the kidneys
ischemia from narrowed lumen of blood vessels that can cause end-stage renal disease
Explain the physiologic effects of sustained chronic hypertension on the eyes
retinopathy, hemorrhages or exudates
Explain the physiologic effects of sustained chronic hypertension on the brain
cerebral vascular disease from cerebral atherosclerosis, TIA/stroke
Explain the physiologic effects of sustained chronic hypertension on the heart
CAD, angina, MI, LV hypertrophy and heart failure
What are the key labs and assessments that identify end organ damage? What are the recommendations for tertiary prevention: how often and how to monitor for organ damage?
Kidneys: serum creatine, proteinuria, microalbuminuria, eGFR
6-12 months
Eye exam
Neuro exam
UA; CBC; Uric acid
BMP (glucose, Na, K, CL, CO2 BUN, Creatinine)
Lipid profile (Total lipids, Triglycerides, HDL, LDL, Cholesterol, Total-to-HDL cholesterol ratio)
6-12 months
ECG for left ventricular hypertrophy, ischemia, or arrhythmias.
1-2 years
USPSTF recommendation for hypertension screening in asymptomatic individuals
BP readings every 3-5 years (18-39 years)
Describe how to use the 5A’s
Ask: open ended questions
Advise: Provide Clear, Personalized Recommendations
Assess: Evaluate Readiness for Change
Assist: Help the patient set realistic, small goals
Arrange: Follow-Up & Monitor Progress
Describe methods used to accurately measure blood pressure in the ambulatory care setting: preparation
Avoid caffeine, exercise, smoking at least 30 minutes before
Empty bladder
No talking while measurement is taken
Remove clothing covering cuff placement
Patient should sit on chair, feet on floor and back supported for > 5 min before taking pressure (not lying or sitting on an exam table)
Describe methods used to accurately measure blood pressure in the ambulatory care setting: technique
Validated device
Support arm
Middle of cuff on upper arm at level of atrium (midpoint of the sternum)
Cuff size: Bladder should encircle 80% of the arm
Can use either stethoscope diaphragm or bell
Describe methods used to accurately measure blood pressure in the ambulatory care setting: taking the measurement
First visit: Record BP in both arms and use arm with higher reading for subsequent measurements
Separate measurement by 1 to 2 minutes
Deflate cuff pressure 2 mmHg per second
Note time of most recent BP medication before taking measurements
Average the readings to estimate BP
Use average of ≥ 2 readings obtained on ≥ 2 occasions
Understand the class of medications that are used to initially treat hypertension
Diuretics: decrease fluid volume
Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin II Receptor Blockers (ARBs): preventing vasoconstriction or promote vasodilation to lower BP
Beta-blockers: not first-line, better for post MI/CHF
Calcium channel blockers: first-line, block calcium influx into vascular smooth muscle and cardiac cells, leading to vasodilation, reduced heart workload, and lower BP
Vasodilators: alpha-blockers; relax and widen blood vessels, reducing blood pressure and improving blood flow
Centrally-acting agents: lower blood pressure by working within the central nervous system (CNS) to reduce sympathetic outflow, leading to decreased heart rate, cardiac output, and vascular resistance
important information to tell an adult just starting antihypertensive medications
medication adherence, lifestyle modifications, potential side effects, and monitoring
side effects of diuretics
fluid/electrolyte imbalances (monitor for hypokalemia)
side effects of beta blockers
decreased heart rate, fatigue, mask hypoglycemia
side effects of ACE Inhibitors
cough, angioedema, hyperkalemia
What questions would you ask the patient to determine if they are experiencing side effects of anti-hypertensive medications?
General well-being
About feeling dizzy, lightheaded, or faint
Fatigue and weakness
Swelling, breathing difficulties
About specific side effects of medications
Understand the four aspects of Motivational Interviewing as reflected in the OARS acronym
Motivational Interviewing (MI) is a patient-centered, goal-oriented counseling style designed to help individuals resolve ambivalence and increase motivation for behavior change
O – Open-Ended Questions
A – Affirmations
R – Reflective Listening
S – Summarizing
Know the stages of change/transtheoretical model. Be able to identify actions that reflect each stage of change
Precontemplation: no intention of change, may be unaware
Contemplation: aware of problem, thinking of changing, no commitment to take action
Preparation: intend to take action soon
Action: modify behavior
Maintenance: maintain behavior and work to prevent relapse
Understand the principles of effective teaching as reflected in the NIH Clear and Simple Communication.
designed to ensure that health information is understandable, accessible, and actionable for diverse audiences
principles focus on simple language, clarity, and active engagement with the patient
Define target audience
Conduct target audience research
Develop concept for product
Develop content and visual design features
Pretest and revise draft materials
SMART goals
Specific
Measurable
Achievable
relevant
time-bound
definition of culture
shared values, beliefs, customs, behaviors, practices, language, traditions, and artifacts that characterize a group of people or society
definition of race
a social construct that categorizes people based on physical characteristics
definition of ethnicity
the shared cultural traits and traditions of a group, often linked to a common ancestry, language, history, and sometimes geographic origin