Microanatomy of Skeletal Muscle Fiber

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31 Terms

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Myoblast

immature muscle cell that forms a muscle fiber

<p>immature muscle cell that forms a muscle fiber</p>
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Skeletal Muscle Fiber contains

Mitochondria, Glycosomes, Myoglobin

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Sarcolemma

plasma membrane of a muscle fiber

<p>plasma membrane of a muscle fiber</p>
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Sarcoplasm

cytoplasm of a muscle cell

<p>cytoplasm of a muscle cell</p>
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Myofibrils

protein structures that make up muscle fibers

<p>protein structures that make up muscle fibers</p>
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Striations

a repeating series of dark and light band

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A bands

Dark regions

Sit between I bands

<p>Dark regions</p><p>Sit between I bands</p>
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M Line

Bisects A Band vertically; Middle of sarcomere

<p>Bisects A Band vertically; Middle of sarcomere</p>
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H Zone

thick filaments only

<p>thick filaments only</p>
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I band

light regions

<p>light regions</p>
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Z Discs

separate one sarcomere from the next

<p>separate one sarcomere from the next</p>
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Sarcomere

Contractile unit of muscle; between Z discs

<p>Contractile unit of muscle; between Z discs</p>
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Myofilaments

actin and myosin

<p>actin and myosin</p>
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Actin

thin filaments

<p>thin filaments</p>
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Actin acts as the

myosin binding site

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troponin and tropomyosin

Ca2+ binding regulatory proteins

<p>Ca2+ binding regulatory proteins</p>
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Thin filaments are anchored

to Z discs

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Myosin

thick filaments

<p>thick filaments</p>
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Myosin contains

globular heads

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Heavy chains

form myosin tail

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Light chains

form myosin globular head to bind actin subunits

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Thick filaments are connected at

M line

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Elastic filament

helps recoil after stretch

<p>helps recoil after stretch</p>
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Dystrophin

Links thin filaments to proteins of sarcolemma

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Sarcoplasmic reticulum

Network of smooth ER

tubules surrounding myofibril

<p>Network of smooth ER</p><p>tubules surrounding myofibril</p>
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Terminal Cisterns

dilated end sacs of the sarcoplasmic reticulum

<p>dilated end sacs of the sarcoplasmic reticulum</p>
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T-tubules

invaginations of the sarcolemma

<p>invaginations of the sarcolemma</p>
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Triad

T-tubule with a terminal cistern on

either side

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Triad relationship

T-tubules and SR membranes linked together by

integral proteins

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T-tubule Funciton

Voltage sensor protein

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SR Membrane function

gated Ca2+ channel