Enzymes and Enzyme Rxns

catalyst

substance that speeds rxns

enzyme

proteins that catalyze biochemical rxns by lowering activation energy by stabilizing transition state

steps to enzymatic reaction

1) substrate binds to active site on enzyme and forms enzyme-substrate complex

2) energy needed for bonds to break/form is decreased

3) products are formed + leave active site and the enzyme catalyzes more rxns

Reaction Rate

measured as the change in the concentration over time or the change in concentration of substrate over time

change in concentration

Δ[P]/time

change in concentration of substrate

Δ[S]/time

Equilibrium

rxn reaches a point where there is no net change

Biochemical rxn reversibility?

most biochemical rxns are reversible

Possible changes to a rxn rate

1) concentration in saturation

2) temp

3) pH

4) Cofactors

5) Competitive Inhibitors

6) Allosteric shape regulators