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Circulatory System
The system that pumps and directs blood through blood vessels to deliver nutrients and oxygen to tissues and remove waste.
Cardiovascular System
Consists of the heart and blood vessels, responsible for systemic and pulmonary circulation.
Atria
The two upper chambers of the heart where blood enters before traveling to the ventricles.
Ventricles
The two lower chambers of the heart that pump blood out to the lungs and the rest of the body.
Myocardium
The cardiac muscle that makes up the bulk of the heart wall, thicker in the ventricles than in the atria.
Pericardium
A fibrous sac surrounding the heart, lined by a serous mesothelium.
Endothelium
A simple squamous epithelium lining blood and lymphatic vessels.
Lymphatic System
A network that returns proteins and interstitial fluid to the bloodstream; does not contain blood.
Pulmonary Circulation
The passage of blood from the heart to the lungs and back to the heart.
Systemic Circulation
The flow of blood from the heart to the rest of the body and back to the heart.
Arteries
Blood vessels that carry blood away from the heart.
Capillaries
The smallest blood vessels, where exchange of oxygen, carbon dioxide, nutrients, and wastes occurs.
Veins
Blood vessels that carry blood back to the heart.
Atrioventricular Valves
Valves between the atria and ventricles that prevent backflow into the atria.
Semilunar Valves
Valves that prevent backflow of blood from the arteries into the ventricles.
Sinoatrial Node
The heart's natural pacemaker that initiates electrical impulses and regulates the heartbeat.
Baroreceptors
Sensory receptors that monitor blood pressure changes, located in carotid arteries and the aortic arch.
Chemoreceptors
Sensory receptors that monitor blood CO2 and O2 levels and pH.
Vasa Vasorum
Small vessels that supply blood to the walls of larger blood vessels.
Precapillary Sphincters
Smooth muscle cells that regulate blood flow into capillary beds.
Continuous Capillaries
Capillaries with a continuous endothelial lining; found in muscle and nervous tissue.
Fenestrated Capillaries
Capillaries with pores in the endothelium, allowing for greater substance exchange; found in kidneys.
Sinusoids
Discontinuous capillaries with larger diameters and gaps between endothelial cells; allow for extensive exchange.
Valves in Veins
Thin folds of tunica intima that help prevent backflow of blood in veins.
Lymphatic Capillaries
Capillaries that collect lymph fluid from tissues and return it to blood circulation.
Pericytes
Contractile cells associated with capillaries that help regulate blood flow.
Connective Tissue in Blood Vessels
Provides structural support and strength to blood vessels; includes collagen and elastic fibers.
Smooth Muscle in Blood Vessels
Muscle tissue that regulates the diameter of blood vessels, affecting blood flow and pressure.
Interstitium
The space between cells in a tissue, where lymphatic capillaries begin.
Postcapillary Venules
The primary site at which white blood cells exit the circulation.
Cardiac Skeleton
Connective tissue framework of the heart that separates atrial and ventricular musculature.
Functional Role of Endothelium
Acts as a semipermeable barrier and secretes factors that regulate clotting and vascular tone.