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Digestive System
Food is first lubricated by saliva in the mouth, where it forms a soft, rounded lump called a bolus. Through the esophagus by means of peristalsis. Then t the stomach, small intestine, large intestine, and it enters as feces into the rectum which leads to expulsion of solid waste
Peristalsis
a unidirectional muscular movement toward the stomach
Stomach
Produces various gastric secretions, including pepsin and hydrochloric acid, to further the digestive process
Small Intestine
Absorption takes place, which produces enzymes that complete the breakdown of proteins to amino acids
Parasympathetic activity speeds up metabolism
Large Intestine
Storage organ for he accumulation of food residue and helps reabsorption of water
Pancreas
Contains enzymes that break down proteins, carbs, and fats. Produces insulin, which facilitates the entry of glucose into bodily tissue
Liver
Produces bile that helps break down fats
Bile stored in the gallbladder and enters the duodenum as needed
Disorders of Digestive System
Gastroenteritis, Diarrhea, Dysentery, Peptic Ulcer, hepatitis, and appendicitis
Gastroenteritis
Inflammation of the lining of the stomach and small intestine
Caused by excessive amounts of food/drink, contaminated food/water, or food poisoning
Symptoms appear approximately 2-4 hours after ingestion and include vomiting, diarrhea, cramps, and nausea
Diarrhea
Watery and frequent bowel movements occurs when the lining of the small and large intestines cannot properly absorb water or digest food
Dysentery
Similar to diarrhea except that mucus, pus, and blood are also secreted
Caused by protozoan that attacks the large intestine or by a bacterial organism
Rarely life threatening in industrialized countries; in developing countries among most common causes of death
Peptic Ulcer
Open sore in the lining of the stomach or duodenum
Results from hypersecretion of hydrochloric acid and occurs when pepsin digest a portion of the stomach wall or duodenum
Appendicitis
Occurs when waste and bacteria accumulate in the appendix
Hepatitis
means “inflammation of the liver” and the disease produces swelling, tenderness, and sometimes permanent damage
Gut microbiome
Includes, fungi, viruses and bacteria
Disturbances have been linked with a variety of physical conditions including, inflammatory bowel disease, asthma, obesity, type 2 diabetes, CVD and autoimmune disorders
Influenced by environmental and lifestyle factors particularly diet and stress
Renal System
Consist of the kidneys, ureters, urinary bladder, and urethra
Kidneys
Regulation of bodily fluids and produce urine
Ureters
Contains smooth muscle which contracts causing peristaltic waves to move urine to the bladder
Urethra
Conducts urine from the bladder out of the body
Urinary System
Regulates bodily fluids by removing surplus water, surplus electrolytes, and waste products generated by the metabolism of food, and surplus acids
Renal System Disorders
Most common are urinary tract infections
Women are especially vulnerable
Nephrons
Basic structural and functional unit of the kidneys
Reproductive System
Development is controlled by the Pituitary Gland
Anterior Pituitary Lobe
Produces the gonadotropic hormones, which control the development of the ovaries and testes
Ovaries
Females have the located in the pelvis
Each month ovaries release an ovum (egg), which is discharged at ovulation into the fallopian tube. If the ovum is not fertilized by sperm it remains in the uterine cavity for about 14 days and then flushed out of the system during menstruation
Produces estrogen and progesterone
Estrogen
Leads to secondary sex characteristics in females including breast and the distribution of body fat and hairs
Progesterone
Is produced in the second half of the menstrual cycle to prepare the body for pregnancy, declines if pregnancy does not occur
Testes
Produces testosterone under control of the anterior pituitary lobe
Brings about sperm production and secondary sex characteristics like growth of beard, deep voice, body hair, skeletal and muscular growth
Disorders of Reproductive System
STDs are the most common and problematic
Includes herpes, gonorrhea, syphilis, genital warts, chlamydia, and AIDs
Others for women include: endometriosis and vaginitus, cysts and fibroids. Menopause is not one- its when a womans reproductive life ends
Endometriosis
Pieces of the endometrial lining of the uterus move into the fallopian tubes or abdominal cavity, grow and spread to other sites
Fetus
Starts life as a single cell, which contains the inherited information from both parents
Nucleus
Where genetic material is in the form of 46 chromosomes
Two are sex chromosomes- one X from mom and an X or Y from dad
Genetic Disorders
Alzheimer’s, cystic fibrosis, and huntington’s disease have a genetic basis
Gene Expression
Process by which the genetic information is turned into a function
Health Psychologists and Genetics
Should people be alerted to genetic risks
Genetic Counseling- helping people decide whether they should be screened and how to cope if they test positive
Direct transmission
Bodily contact- handshaking, kissing, and sexual intercourse
Indirect transmission
Microbes are passed via airborne particles, dust, water, soil, or food. Ex Influenza
Biological Transmission
A transmitting agent, like mosquito, picks up microbes, changes them into a form conducive to growth in the body and passes them onto a human. Ex: Yellow Fever
Mechanical Transmission
Passage of microbe to a person by means of a carrier that is not directly involved in the disease process. Dirty hands, bad water, rats, mice, flies can be implicated
Infection
Once a microbe reaches the body it penetrates into bodily tissue via skin, throat, and respiratory tract, digestive tract, or genitourinary tract.
Whether the microbes gain foothold to produce this depends on:
The number of organisms
The virulence of the organisms
The bodies defensive capacities
Virulence
Determined by aggressiveness (ability to resist bodies defense) and toxigenicity (ability to produce poisons)
Course of Infection
Incubation Period
Nonspecific Symptoms
Acute Phase
Period of Resolution
Incubation Period
Time the infection is contracted and the time the symptoms appear
Nonspecific Symptoms
(maybe) precedes onset of the disorders. The immune system an initial response to the pathogen and releasing cytokines that coordinate immune and behavioral response
Acute Phase
Illness and Symptoms are at their height
Period of Resolution
Organisms are expelled from the mouth and nose in saliva and respiratory secretions and the digestive and genitourinary system in feces and urine
Immunity
The bodies resistance to invading organisms
Natural Immunity
Passed from mother to child at birth (temporary) or through disease (measles, have it once and unlikely again)
Artificial Immunity
Acquired through vaccinations and inoculations
Non Specific Immune Mechanisms
General set of responses to any kind of infection or disorder
Specific Immune Mechanisms
Always acquired after birth, fight particular microorganisms and their toxins, by infection or vaccinations
Slower and more specific than natural immunity
Granulocytes
Largest group of cells involved in natural immunity
Includes neutrophils
Neutrophils
Congregate at the sites of injury or infection and destroy pathogens by ingesting them or releasing toxic substances
Macrophages
Important cell in natural immunity that release cytokines that lead to inflammation and fever and promote wound healing
Natural Killer Cells
Involved in natural immunity and they recognize “nonself” material and lyse (breakup and disintegrate) those cells by releasing toxic and substances
Phagocytosis
Process by which certain white blood cells (phagocytes) ingest microbes
Overproduce when there is a bodily infection, so large numbers can be sent to the site to ingest foreign particles
Antimicrobial Substances
Chemicals produced by the body that kill invading microorganisms. Ex: Interferon, hydrochloric acid
Humoral Immunity
Directed against extracellular pathogens mediated by B lymphocytes
Cell Mediated Immunity
Involving T lymphocytes from the thymus gland, is directed against intracellular pathogens
Immune System Disorders
AIDS and Autoimmunity
AIDs
Progressive impairment of immunity
Autoimmunity
Occurs when the body attacks the bodies own tissues
Ex: Type 1 diabetes, rheumatoid Arthritis, Inflammatory bowel disease and lupus
Autoimmune Disease
The body fails to recognize its own tissues and produces antibodies to fight it