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Why is therapeutic modalities for pain valuable tools?
-Reduces nociception
-Calms down the nervous system
-Improves the pain experience
What are some considerations for therapeutic modalities for pain/
-Passive treatment
-Patient beliefs
-Improved self-efficacy
-Utilized with symptom-provoking activities
What are the 2 mechanisms behind therapeutic modalities for pain?
-Altering of nociceptive info from the periphery
-Increased production of endogenous opioids
What is TENS for pain?
Application of low-voltage electrical current for pain relief
What is IFC for pain?
Application of 2 medium frequency currents to produce amplitude-modulated low frequency for pain relief
What are the 2 mechanisms of TENS and IFC?
-Increases central inhibition (gate control theory)
-Reduces central excitability (endogenous opioid theory)
What 2 endogenous opioids does high-frequency TENS for analgesia activate?
Beta-Endorphin and Enkephalin
What 2 things does high-frequency tens for analgesia release?
GABA and acetylcholine
High-frequency TENS for analgesia decreases the release of what excitatory neurotransmitters?
-Glutamate
-Cytokines
-Substance P
High Frequency TENS increases activity peripheral alpha-2a-adrenergic receptors, such as ____
Norepinephrine
Low-Frequency TENS activates endogenous opioids beta-endorphins, enkephalin, and ____
seratonin
Strong non-painful TENS’ stimulation ____ is critical to therapeutic success
intensity
What is the clinical utility of TENS?
-Low risk
-Non-addictive
-Cost-effective
-Over the counter
-Self efficacy
True or False: TENS should be used at the highest tolerable intensity
True
TENS is used to restore _____ and to reduce central excitability
central inhibition
For the greatest effects, where should the electrodes be placed
At the site of injury
What is the proposed mechanism behind thermal agents?
Change in tissue temperatures alters cellular and physiological function
Thermal agents have what type of pain modulation effect for the following:
-pain thresholds in healthy controls
-peripheral nociceptor activation
-nerve conduction
-Increase
-Decrease
-Decrease
What is the proposed mechanism behind ultrasound?
Acoustic energy for tissue healing, anti-inflammatory effects
How does ultrasound affect pain modulation for the following:
Peripheral nociceptor activation
Nerve conduction
Decreases both
True or False: Ultrasound has limited and inconclusive evidence for pain management
True
What pain modulation effects does low-intensity laser have for the following:
Release of substance P
Release of B-Endorphins
Decrease
Increase
What are some considerations for manual therapy?
-Pain mechanisms
-Models
-Locus of control
-Language
-Patient expectations
-PNE + manual therapy
What are the central mechanisms of massage therapy?
-Descending inhibitory pathways
-Stress reduction
-Potentially lower cortisol levels
What are the peripheral mechanisms of massage therapy?
-Increase expression of tissue healing genes
-Decrease expression of inflammatory genes
How does high thrust joint manipulation help pain?
Increases pain threshold
Decreases motor neuron excitability
What is the “physical movement of the nervous system”?
Neurodynamics
What are the three elements of neurodynamics?
Space
Movement
Blood
What are the three bottom lines with manual therapy
-Decreases mechanical/chemical irritants that activate nociceptors
-Non-nociceptive input to proprioceptors
-Activate central descending mechanisms to decrease pain
True or False: Manual therapy has no negative evidence
True
What are some contextual factors to the delivery of manual therapy?
-Treatment factors
-Patient/therapist characteristics
-Patient-provider relationship
-Healthcare setting
How does an impaired “body map” affect patients with chronic pain
-creates a “smudging” of the homunculus
-Disrupted body image
-Decreased tactile acuity in area of usual pain
What is graded motor imagery?
Various synaptic exercises aimed at restoring altered body maps
What are some techniques behind graded motor imagery?
-Normalize laterality
-Motor imagery
-Mirror therapy
-Sensory discrimination
What is the goal of laterality retraining?
Cortical reorganization in the homunculus
What is the goal of motor imagery?
Solidifying brain maps and run those maps with minimal pain, without actual movement
What are some strategies behind motor imagery?
-Think about the movement
-Visualize the activity
-Progress when can do with little to no pain
What is the goal of sensory discrimination?
Sharpen the body map on or close to the affected area
-Potential linkage of sensory & proprioceptive neural circuits to refresh body maps
What is the goal of mirror therapy?
Provide a visual cue that movement is occurring with little to no pain
What are some strategies of mirror therapy?
-Use mirrors to trick the brain
-Uninvolved extremity does movement and the mirror projects movement of involved extremity
-All about exposure
-Progress to active, graded exposure