PTCB Review

absorption

one drug may alter the GI pH, motility or binding of another drug, affecting its bioavailability

distribution

competition of drugs for protein binding sites. ex: warfarin and aspirin both bind to plasma proteins. If taken together, can increase risk of bleeding

metabolism

drugs induce or inhibit enzymes that metabolize other drugs

excretion

drugs can affect renal excretion of other drug

additive

combination effect of 2 drugs is = to sum of their individual effects. ex: alc and benzodiazepenes both depress CNS, leading to increased sedation

synergistic

combined effect is greater than sum of individual effects

antagonistic

one drug reduces the effect of another

What is the active ingredient of the medicine, Prozac?

fluoxetine

A medicine with an expiration date of 09/2020 expires on which date?

09/30/2020

Nitrofurantoin, a drug used to treat urinary tract infections, is known to discolor urine what color?

Brown

HEPA filters found within laminar hoods remove particles that are at least what size?

0.3 microns

Which of these is an automated dispensing cabinet that allows for the billing of patients who receive medicines?

Omnicell

Which of these is the safest and most appropriate way to represent a number, one that complies with FDA regulations?

0.5

Which of these drug classes must be dispensed alongside a drug accountability record (DUR)?

investigational products

Which of the following laws established the protocol that drugs are identified and reported using the NDC?

drug listing act

Alendronate is used in the treatment of which condition?

osteoporosis

Geometric dilution” is required in which of these cases?

quantity of drug is small relative to total vehicle

What is the mechanism of action of albuterol and salmeterol?

Beta 2 receptor agonism

Which of the following drugs is an example of a potassium-sparing diuretic?

Amiloride

In the pharmacy, how frequently should backups be taken of database files?

every day

Which of the following is NOT used to reduce medication errors?

Medication therapy review

Which of these conditions results from a deficiency of dopamine within the nigrostriatal pathway?

Parkinson’s disease

Which of the following terms is used to describe any unintended harm that results from the use of a medicine?

Adverse drug reaction

Which of the following statements about Medicaid is true?

Designed for patients with low incomes

H1 antagonists, such as loratadine, are used in the treatment of which condition?

Allergies