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What are the FIVE things that can help you classification of a virus?
Nature and sequence of viral genome
Symmetry of protein shell (capsid)
Presence or absence of lipid membrane (envelope)
Size of virus particle
Replication characteristics and disease
Today most of the viruses is classified by what?
Nature and sequence of viral genome
What is the order of taxonomy?
Realm
Kingdom
Phylum
Class
Order
Family
Genus
Species
What are the FIVE things that can make up the virus's structure?
Nucleic Acid
Capsid and Nucleocapsid
Envelope
Envelope glycoproteins or
Peplomers (spike proteins)
Matrix proteins (tegument)
The viral genome can be made up of what TWO things?
DNA
RNA
Describe RNA to me
Single stranded
Linear
Segmented
ssRNA positive
Describe DNA to me.
Double stranded
Circular
Non segmented
negative sense strand
What are the TWO types of capsid symmetry viruses can have?
icosahedral symmetry
helical symmetry
What does it mean to have helical symmetry?
arranged in a helix
What does it mean to have icosahedral symmetry?
a geometric shape with 20 sides, each composed of an equilateral triangle,
What are the TWO broad functions of structural proteins?
protection of the genome
delivery of the genome
How do structural proteins help to protect the genome? (3)
Assembly of a stable protective protein shell
Specific recognition and packaging of the nucleic acid
Interaction with host cell membranes to form the envelope and exit the cell
How do structural proteins help with delivery to the genome? ( 4 steps)
Bind to host cell receptors
Uncoating of the genome
Fusion with cell membranes
Transport of genome to the appropriate site